Two-way selection for male recombination over seven intervals of the third chromosome in Drosophila melanogaster was practiced for nine generations followed by relaxed selection for five generations. Significant responses in both directions were observed but these mainly occurred in early generations in the low line and in later generations in the high line. Divergence of male recombination fre...

Previous studies have indicated that recombination near the third chromosome centromere is associated with negative chromosome interference, a phenomenon for which GREEN (1975) and SINCLAIR (1975) suggested gene conversion as a possible mechanism. In this report, we demonstrate that negative chromosome interference is still observed when deficiencies or translocation breakpoints are scored as t...

The function of thefrizzled V;) locus is required to coordinate the cytoskeletons of pupal epidermal cells so that a parallel array of cuticular hairs and bristles is produced. We report here the molecular cloning and characterization of the fz locus. The locus is very large. Mutations that inactivate the gene are spread over 100 kb of genomic DNA. The major mRNA product of the gene is a 4-kb R...

In Drosophila melanogaster, the study of trans-acting modifier mutations of positioneffect variegation and Polycomb group (PC-G) genes have been useful tools to investigate genes involved in chromatin structure. We have cloned a modifier gene, Suppesssm of zeste 5 (Su(z)S), which encodes Sadenosylmethionine synthetase, and we present here molecular results and data concerning its expression in ...

In Norway, there was considerable overlap between the poor house, workhouse, and correctional facilities. An assemblage of human skeletal remains from Oslo's House Correction cemetery, largely comprised individuals disturbed during municipal development in 1989, consists c. 314 who died as inmates or residents; many were disabled elderly. Although names recorded at death, cemetery lacked grave ...

The eighteenth-century “discovery” of the buried cities of Herculaneum and Pompeii revolutionized the way in which individuals thought about their relationship with the ancient world. The accounts of British visitors between 1738 and the end of the century reflect a new historical sensibility, one predicated upon the extraordinary proximity between present and past that these sites seemed to pr...