Nanomanipulation of biomolecules by using single-molecule methods and computer simulations has made it possible to visualize the energy landscape of biomolecules and the structures that are sampled during the folding process. We use simulations and single-molecule force spectroscopy to map the complex energy landscape of GFP that is used as a marker in cell biology and biotechnology. By enginee...

The Norwegian Biotechnology Advisory Board is an independent body appointed by the Norwegian government and was established in 1991. The Board is founded in the Act relating to the application of biotechnology in medicine and the Act relating to the production and use of genetically modifi ed organisms. The main tasks of the Norwegian Biotechnology Advisory Board are to identify and examine the...

Recombinant protein expression often presents a bottleneck for the production of proteins for use in many areas of animal-cell biotechnology. Difficult-to-express proteins require the generation of numerous expression constructs, where popular prokaryotic screening systems often fail to identify expression of multi domain or full-length protein constructs. Post-translational modified mammalian ...

One of the latest and most controversial areas of science is biotechnology. Genetic engineering concerns with the manipulation of DNA molecules to modify plants, animals and other creatures. Scientists are now able to isolate a gene or genome in an animal or plant to another one, based on the traits they want to transfer. The movement of a gene from a living creature to another one is called th...

The development of biomolecular devices that interface with biological systems to reveal new insights and produce novel functions is one of the defining goals of synthetic biology. Our lab previously described a synthetic, riboregulator system that affords for modular, tunable, and tight control of gene expression in vivo. Here we highlight several experimental advantages unique to this RNA-bas...

Stilbenoids are well-known phytoalexins in the group of polyphenolic compounds. Because their potent bioactivities, including antioxidant, antityrosinase, photoprotective, and antibacterial activities, stilbenoids utilized as pharmaceutical active ingredient cosmetic products. Thus, demand for industry is increasing. The main sources plants. Although plants green sustainable source materials, s...