نتایج جستجو برای: granulocytes

تعداد نتایج: 5616  

Journal: :Infection and immunity 2002
Hinda J Ahmed Catharina Johansson Liselott A Svensson Karin Ahlman Margareta Verdrengh Teresa Lagergård

We investigated the phagocytosis of Haemophilus ducreyi both in vitro and in vivo. Human granulocyte and monocyte phagocytosis of opsonized and nonopsonized, fluorescence-labeled H. ducreyi was assessed by flow cytometry. Both Escherichia coli and noncapsulated H. influenzae were included as controls. The maximal percentage of granulocytes taken up by H. ducreyi was 35% after 90 min. In contras...

Journal: :Journal of immunology 2003
Mamiko Miyamoto Masashi Emoto Yoshiko Emoto Volker Brinkmann Izumi Yoshizawa Peter Seiler Peter Aichele Eiji Kita Stefan H E Kaufmann

LFA-1 (CD11a/CD18) plays a crucial role in various inflammatory responses. In this study, we show that LFA-1(-/-) mice are far more resistant to Listeria monocytogenes infection than LFA-1(+/-) mice. Consistent with this, we found the following: 1) the numbers of granulocytes infiltrating the liver were markedly higher in LFA-1(-/-) mice than in LFA-1(+/-) mice, 2) increased antilisterial resis...

Journal: :Blood 1977
C A Schiffer F T Sanel V B Young J Aisner

The effects of the cationic anesthetic agents tetracaine and lidocaine on granulocyte function, morphology, and adherence to nylon fibers were studied in an attempt to improve current methods of granulocyte collection by filtration leukapheresis (FL). When dissolved in acid-citrate-dextrose (ACD) plasma, these drugs significantly increased granulocyte elution from the fibers in a dose-related f...

Journal: :Annals of the rheumatic diseases 2005
O Kowal-Bielecka K Kowal J Rojewska A Bodzenta-Lukaszyk Z Siergiejko M Sierakowska S Sierakowski

OBJECTIVES To determine whether cyclophosphamide is beneficial for patients with scleroderma lung disease (SLD). METHODS The effect of 6 months' treatment with intravenous cyclophosphamide on the functional capacity of patients, lung function tests, high resolution computed tomography of the lungs, and cytology of bronchoalveolar lavage was evaluated in 21 patients with SLD. RESULTS The tre...

Journal: :Journal of clinical pathology 1989
D Pace L Morrison J N Bulmer

The proliferative activity in endometrial stromal granulocytes was studied using two approaches. Firstly, mitotic activity was studied in paraffin wax embedded sections of normal non-pregnant endometrium and early pregnancy decidua stained with phloxine-tartrazine. Secondly, the monoclonal antibody Ki67 was applied to cryostat sections of similar tissues. Endometrial stromal granulocytes were i...

Journal: :The Journal of clinical investigation 1962
R C MECHANIC E FREI M LANDY W W SMITH

Bacterial endotoxins injected intravenously in small doses into animals and man produce, among other effects, a transient granulocytopenia followed by a marked granulocytosis (1-7). Several comprehensive reviews have recently appeared which deal with the wide spectrum of biologic effects of these substances, including their relationship to the pathogenesis of fever, the development of tolerance...

Journal: :Blood 1974
J M Mishler D C Hadlock I E Fortuny R W Nicora J J McCullough

A total of 67 leukaphereses were performed with the continuous-flow centrifuge (CFC) on 27 healthy donors for the purpose of obtaining increased yields of granulocytes for infusion into septic patients with acute leukemia accompanied by severe granulocytopenia. The addition of hydroxyethyl starch (HES) to the input line of the CFC significantly (p < 0.005) increased the total number of leukocyt...

2008
Mimi HØIER-MADSEN Jan HOLM Steen I. HANSEN

Synopsis The high-affinity FBP/FR (folate-binding protein/folate receptor) is expressed in three isoforms. FRα and FRβ are attached to cell membranes by hydrophobic GPI (glycosylphosphatidylinositol) anchors, whereas FBPγ is a secretory protein. Mature neutrophil granulocytes contain a non-functional FRβ on the surface, and, in addition, nanomolar concentrations of a secretory functional FBP (2...

Journal: :Annals of clinical and laboratory science 1981
K C Poon P I Liu J J Chen C C Hong R C Allen

A modified method of Boyum's technique to isolate granulocytes and lymphocytes from human blood is described. The granulocytes and the lymphocytes separated by this isolation procedure are highly pure, viable, and in sufficient number for subsequent isoelectric focusing studies. Different proteins have been separated by isoelectric focusing. This technique can be useful in the investigation of ...

Journal: : 2022

Formyl peptide receptors (FPRs) are an important part of innate immunity involved in antimicrobial phagocyte functions such as chemotaxis, secretory degranulation, and respiratory burst. These responses observed both acute systemic chronic inflammation. Abundant or constant release pro-inflammatory ligands leads to the pre-activation phagocytes when subsequent stimulation induces more intense c...

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