Autonomic and sensory ganglion cells in the senile dog contain a deposition of PAS-positive substances which has been shown to be mucoprotein in nature. Data are presented to show that this PAS-positive mucoprotein can be demonstrated by metachromatic staining with toluidine blue after the mucoprotein is sulfated. This procedure indicates that mucoprotein is also present in a granular form in a...

OBJECTIVE To evaluate with immunohistochemical methods 5 atypical melanocytic conjunctival lesions. METHODS This was a retrospective clinicoimmunopathologic study. Routine histochemical staining was performed with multiparametric immunohistochemical analysis with monoclonal antibodies immunoreacted on paraffin sections to identify the following cell antigens: S-100, MART-1, HMB-45, CD45, CD68...

We examined the morphological consequences of focal irradiation of the cerebellum with successive daily doses of low-level X-ray in lo-, 30-, and 90-dayold rats. The subtotally eliminated external granular layer was reconstituted by 10 days in animals exposed to l-2 X 200 r and there was little or no reduction in the total area of the cerebellar cortex and its various layers at 30 and 90 days. ...

Cultured fibroblasts or epithelial cells derived from Xenopus laevis embryos were directly frozen, freeze-substituted by an improved method, and then either critical-point-dried and viewed as whole mounts, or embedded and thin sectioned. In thin regions of these cells, where ice crystal artifacts are absent, the cytoplasm consisted of a dense, highly interconnected meshwork of filaments, embedd...

Hyperoxia is known to injure tissues and cells (1) . In a series of papers the quantitative influence of hyperoxia on some aspects of lung ultrastructure was elucidated (2-4) . These studies revealed that hyperoxia resulted in rapid destruction of the pulmonary capillaries, a thickening of the air-blood barrier, and, eventually, a repopulation of the alveolar epithelium by granular pneumocytes ...

INTRODUCTION Congenital oral granular cell tumour of the newborn is an uncommon benign tumour of uncertain origin. The typical clinical appearance is of a single nodule occurring on the anterior maxillary ridge. In 10% of cases there are multiple lesions. The occurrence of congenital epulis in non-Caucasians is rare. CASE PRESENTATION Two firm pedunculated nodular lesions were noticed in the ...

Hyperoxia is known to injure tissues and cells (1) . In a series of papers the quantitative influence of hyperoxia on some aspects of lung ultrastructure was elucidated (2-4) . These studies revealed that hyperoxia resulted in rapid destruction of the pulmonary capillaries, a thickening of the air-blood barrier, and, eventually, a repopulation of the alveolar epithelium by granular pneumocytes ...

Pulmonary granular cells tumors (CGT) are rare tumors, that derive from Schwann cells. In the tracheobronchial and pulmonary tree, they remain a diagnostic challenge. There no well-established criteria to differentiate between benign, atypical, malignant GCT. Moreover, its real frequency in respiratory tract is still unknown. Here, we represent 2 cases of bronchial lung GCTs. We aim highlight a...

A cerebral granular cell tumor is described in a 6-year-old, short-haired, female cat. The tumor was observed above the corpus callosum and completely infiltrating the third ventricle. Histologic examination revealed that the tumor was characterized by large cells containing densely packed intracytoplasmic granules and expressed psammoma body-like patterns and cholesterinic degeneration. Immuno...

The skin of Xenopus laevis contains a soluble beta-galactoside-binding lectin with a approximately 16,000-mol-wt subunit. It resembles similar lectins purified from a variety of tissues from other vertebrates, and differs from two other soluble X. laevis lectins from oocytes and serum that bind alpha-galactosides. The skin lectin is concentrated in the cytoplasm of granular gland and mucous gla...