This comparatively new method of treatment has been used in various centres, with satisfactory results in the last two to three years. Conditions which are suitable for treatment are lichen planus, lichen simplex chronicus, discoid lupus erythematosus, granuloma annulare, alopecia areata, alopecia totalis, psoriasis, sarcoid of Boeck, keloid, eczema of various types, acute dermatitis medicament...

Transepidermal elimination (TE) is a mechanism whereby foreign or altered constituents can be removed from the dermis. This process involves unique morphologic alterations of the epidermis, which forms a channel and thereby facilitates extrusion of the desired dermal components. The phenomenon of TE may occur as a primary process characterizing disorders, such as elastosis perforans serpiginosa...

Kowloon Bay Integrated Treatment Centre, 9/F Kowloon Bay Health Centre, 9 Kai Yan Street, Kowloon Bay, Kowloon, Hong Kong This is a case report of a 20-month-old boy who presented with multiple asymptomatic nodules on the left pretibial area. He had no history of diabetes or other systemic diseases. Family history was unremarkable. Skin biopsy showed palisading granuloma in deep dermis and subc...

We report the case of a 44-year-old Indian male patient who presented with mildly tender isolated papular lesions confined to the palms of the hands and soles of the feet. The histopathology was characteristic of granuloma annulare. There was an excellent response with 4-week treatment with a potent topical steroid ointment and no recurrence was reported at the follow-up one year later. This re...

Skin lesions accompanying hematological malignancies can be formed due to either direct tumor infiltration of the skin or indirect effects. Indirectly developing lesions may be a component of paraneoplastic syndrome. Erythema annulare centrifugum (EAC) is considered to be a hypersensitivity reaction developed against various antigens associated with infections, drugs, and endocrine diseases. EA...

ransepidermal elimination is a disorder in which T dermal stimuli profoundly effect the behavior and structure of the overlying epidermis. Briefly, there are two categories of disorders: the first are primary dermatoses and consist of elastosis perforans serpiginosa and reactive perforating collagenosis; the second group originates from alterations of dermal constituents in preexisting disorder...

Several dermatoses are routinely associated with diabetes mellitus, especially in patients with chronic disease. This relationship can be easily proven in some skin disorders, but it is not so clear in others. Dermatoses such necrobiosis lipoidica, granuloma annulare, acanthosis nigricans and others are discussed in this text, with an emphasis on proven link with the diabetes or not, disease id...

BACKGROUND Cutis laxa is a rare dermatosis that can be inherited or acquired. The acquired form is rare and has been associated with various conditions, including multiple myeloma, monoclonal gammopathy of undetermined significance, and heavy chain deposition disease. OBSERVATIONS We describe a 48-year-old man who developed generalized cutis laxa over a 4-year duration. There were no precedin...

BACKGROUND Granuloma annulare is a granulomatous disease of unknown etiology. Various therapies have been tried in disseminated granuloma annulare (DGA), including corticosteroids, several variants of psoralen plus ultraviolet-A radiation, ultraviolet- A1 radiation, systemic retinoids, and dapsone, with variable success. We report a patient with recalcitrant DGA who was treated with fumaric aci...