Naphthyridones that were recently described as a class of translation inhibitors in gram-positive bacteria mediate their mode of action via GyrA in Haemophilus influenzae and Escherichia coli. These are the first examples of compounds in which modes of action in different bacterial pathogens are mediated through widely different targets.

the presence of antibacterial activity in bovine β-lactoglobulin and in α-lactalbumin hydrolysates was investigated. the plasmin-digest of β-lactoglobulin (pdβ) and of α-lactalbumin (pdα) were fractionated, using reversed phase high performance liquid chromatography. the antibacterial activity of β-lactoglobulin, α-lactalbumin, nisin, plasmin, pdβ and pdα were in vitro tested against pathogenic...

The Gram stain classifies most bacteria into one of two groups, Gram-negative or Gram-positive, based on the composition their cell walls [...]

The Danish microbiologist Hans Christian Gram developed a staining technique (1884) that classifies most bacteria into two large groups that are referred to eponymously, as Gram-positive and Gram-negative bacteria (1). His stain is still used in medical microbiology labs today, and because of its explanatory power, this classification is the most commonly used descriptor of a particular bacteri...