background: hepatitis activity index (hai) and fibrosing stage are two important findings during the evaluation of liver samples in patients with chronic hepatitis b. the aim of this study was to determine the hai and fibrosing stage in patients with anti-hbe positive chronic hepatitis b. methods: liver biopsy slides of 72 patients were evaluated at the department of pathology in two teaching h...

background : cd117 is a thyrosin kinase receptor encoded by c-kit proto-oncogene. it is expressed during normal development in some tissues and also in a subset of neoplasia especially gastrointestinal stromal tumors   (gists). treatment with thyrosin kinase inhibitors (e.g., imatinib) is useful in cd117- positive gists. the goal of this study is to investigate the expression of cd117 in glial ...

Mobilization of hematopoietic progenitors in 15 untreated patients with low-grade myelodysplastic syndrome (IPSS score < or =1) resulted in poor yields in seven patients; moreover, mobilized cells had abnormal cytogenetics and defective in vitro growth. Only three out of 15 patients had adequate progenitor cell collections for potential use in autologous transplantation.

Six of seven grade school students using Voice Type Voice Data entry systems experienced a variety of unexpected learning. Improvements in speech, breathing patterns, stamina and overall communication were noted in six of the participants. This paper looks at the partnership that produced this result as well as case synopsis for six of the users

A three year retrospective study was done to study snakebite envenomation among Kashmiri children. Ten children were admitted with snakebite. Snakebite was vasculotoxic in seven and mixed in two. Levantine viper bites were seen in five who had Grade 3 bites with severe local signs, severe coagulopathy and hypotension. Both environmental risk and seasonal incidence was observed.

BACKGROUND The aim was to determine the maximum tolerable dose of oxaliplatin added to (oral) 5FU in irresectable rectal cancer. PATIENTS AND METHODS Nineteen patients were treated; 13 patients received 5FU/LV and 6 patients capecitabine. Oxaliplatin was administered on days 1 and 29 at dose levels 85 and 130 mg/m2. Four to seven weeks thereafter, surgery was performed. RESULTS In 6 patient...

Results: There were 124 men and 25 women with a mean age of 35 (16 to 72) years. Fractures were caused in the majority of cases (130 cases, 87.2%) by traffic accidents. Fractures were classified according to Cauchoix system into 96 grade I, 55 grade II, and 3 grade III. The duration of follow-up averaged nine (3 to 25) months. Infections (softtissue and bone) were encountered in 30 (19.5%) frac...

PURPOSE We determine the significance of c-erbB-2 and p53 gene in the progression of renal pelvic and ureteral carcinomas. METHODS Overexpression of c-erbB-2 and p53 oncoprotein was investigated using immunohistochemical staining with reference to pathological features. The expression of Ki-67 antigen was also studied as a proliferation marker. RESULTS Forty-seven cases were examined, and t...

The multiple tumor suppressor gene l (MTS1) located on chromosome 9p has recently been implicated as a candidate tumor suppressor gene in many different tumor types. Cytogenetic analysis and deletion mapping studies have revealed that deletion of chromosome 9p occurs in a signif icant number of primary human astrocytomas. Using multiplex PCR with primers for exon 2 of MISI and for D9S196 from c...

The case notes of 34 patients undergoing rehabilitative facial nerve surgery between 1978 and 1994 were retrospectively examined. Thirteen patients underwent facio-hypoglossal transposition with six achieving a facial nerve grade of IV (House-Brackmann scale) at 24 months post-surgery. Twelve patients underwent cable grafting of the facial nerve defect. Of these, 10 achieved a grade III result ...