A 69-year-old man was admitted for resection of rectal adenocarcinoma diagnosed by colonoscopy. Preoperative computed tomography scan and abdominal ultrasonography revealed bilateral renal tumors measuring up to 2 and 2.8 cm in largest diameter, respectively. The patient underwent partial colectomy and bilateral partial nephrectomy. Microscopically, rectal adenocarcinoma penetrated the submucos...

OBJECTIVES To validate with an independent study that simple atrophy/postatrophic hyperplastic lesions (proliferative inflammatory atrophy [PIA]) often merge directly with high-grade prostatic intraepithelial neoplasia (PIN). METHODS Using radical prostatectomies (n =14), all high-grade PIN and adenocarcinoma lesions were identified. We examined the two-dimensional topographic relationship be...

PURPOSE To present the techniques and preliminary outcomes of ultrasound-based image-guided intensity-modulated radiotherapy (IG-IMRT) for pancreatic cancer. MATERIALS AND METHODS Retrospective analysis of 41 patients treated between November 2000 and March 2005 with IG-IMRT to mean total doses of 55 Gy (range, 45-64 Gy). We analyzed the clinical feasibility of IG-IMRT, dosimetric parameters,...

BACKGROUND This study was aimed at evaluating the correlation between Hepatocyte paraffin 1 (Hep par 1) and colorectal cancer. METHODS To this end, 50 intestinal biopsies were analyzed including 10 colorectal polyps with low grade dysplasia, 10 with high grade dysplasia, 10 colorectal adenocarcinomas, 10 specimens of normal ileum and 10 of normal colon mucosa. Tissue sections were immunostain...

MLH1 immunoreactivity in prostatic adenocarcinoma. The increased MLH1 expression in the precursor lesion HGPIN suggests a role of MLH1 in prostatic carcinogenesis. However, its expression may not be related to the aggressiveness of prostatic cancer, because the intensity of immunoreactivity is similar in both intermediate and high-grade prostatic adenocarcinoma. Lastly, we have demonstrated the...

<p class="abstract">Polymorphous low-grade adenocarcinoma (PLGA) is an infrequent type of malignant epithelial tumor that occurs almost exclusively in minor salivary glands. It commonly presents women between the sixth and eighth decade life, usually as asymptomatic mass long evolution slow growth oral cavity but can erode infiltrate adjacent bone. We present 2 case reports review literat...

The purposes of this study were to evaluate the prognostic significance of Glut-1 expression in patients with pancreatic ductal adenocarcinoma, and to analyse its expression in pancreatic intraepithelial neoplasias (PanIN) and non invasive intraductal papillary mucinous neoplasms (IPMN). Glut-1 expression was studied by immunohistochemistry in 60 pancreatic ductal adenocarcinomas and scored on ...