This work aims the functionalization of reduced graphene oxide nanoplatelets with chitosan (G-chitosan) and also with poly(styrenesulfonic acid) (GPSS), thus forming stable, dispersed aqueous solutions. G-chitosan and GPSS solutions allowed the layer-by-layer (LbL) film formation with glucose oxidase (GOx), establishing multilayered nanostructures with elevated control in thickness and morpholo...

An electrochemical response of glucose and lactate biosensors which were prepared by coating a platinum electrode with a thin film composed of concanavalin A and mannose-labeled glucose oxidase (GOx) or lactate oxidase (LOx) was evaluated in the presence of ferrocene derivatives as electron mediator. Both glucose and lactate biosensors showed catalytic current to glucose and lactate, respective...

Aptamer based ATP binding leads to the release of the co-factor FAD, which acts as a trigger to 'turn-on' the activity of apo-GOx and thus generates a measurable response.

This study reports the first approach of immobilizing a redox (glucose oxidase-GOx) enzyme on amino functional group-integrated tailor-made textile (polyester nonwoven fabric-PF) support matrix. To achieve that, polyethylenimine if not chitosan was chemically grafted plasma (with O2/N2 gas)-activated PF before GOx through physical adsorption. Diverse qualitative and quantitative characterizatio...

Synergistic strategies by combining nanoreactors and prodrugs hold tremendous potential in anticancer treatment. However, precise death of target cancer cells remains a significant challenge due to the absence an elaborate targeting strategy. Here, dual-targeting approach that combines action H2O2-producing folate receptor-targeted with cyclooxygenase-2 (COX-2) targeted prodrug is reported. A f...

We investigate how distributed denial-of-service (DDoS) attacks and other disruptions affect the Bitcoin ecosystem. In particular, we investigate the impact of shocks on trading activity at the leading Mt. Gox exchange between April 2011 and November 2013. We find that following DDoS attacks on Mt. Gox, the number of large trades on the exchange fell sharply. In particular, the distribution of ...

The maintenance of the immune system can be costly, and a lack of dietary protein can increase the susceptibility of organisms to disease. However, few studies have investigated the relationship between protein nutrition and immunity in insects. Here, we tested in honeybees (Apis mellifera) whether dietary protein quantity (monofloral pollen) and diet diversity (polyfloral pollen) can shape bas...

This article reports on a study on fluorescence adenosine triphosphate (ATP) detection by InP/ZnS quantum dots (QDs). We present a spectroscopic analysis displaying the effect of enzymatic reactions of glucose oxidase (GOX) and hexokinase (HEX) on the InP/ZnS quantum dots at physiological pH. The InP/ZnS quantum dots act as glucose sensors in the presence of GOX, Glu and ATP, and their luminesc...

In this study, a biosensor, based on a glucose oxidase (GOx) immobilized, carbon-coated tin sulfide (SnS) assembled on a glass carbon electrode (GCE) was developed, and its direct electrochemistry was investigated. The carbon coated SnS (C-SnS) nanoparticle was prepared through a simple two-step process, using hydrothermal and chemical vapor deposition methods. The large reactive surface area a...