Biology is known for is being rather unpredictable; people often tell us we are a bit 'quirky', and they generally mean this as a compliment. This likely relates to the 'pleasure of novelty': it is a common experience that when something, even a great work of art, is experienced too often within a short period of time, the pleasure evoked strongly diminishes. The idea of 'fun' in work does not ...

Consider a politician who has to take two sequential decisions during his term in office. For each decision, the politician faces a trade-off between taking what he believes to be the decision that generates a public benefit, thus increasing his chances of re-election, and taking the decision that increases his private gain but is likely to decrease his chances of re-election. In our results we...

Good Clinical Practice (GCP) is an international ethical and scientific quality standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical trials involving the participation of human subjects. Compliance with this standard provides public assurance that the rights, safety, integrity and confidentiality and well being of trial subjects are ...

Good Clinical Practice (GCP) is an international ethical and scientific quality standard for the design, conduct, performance, monitoring, auditing, recording, analyses and reporting of clinical trials. It also serves to protect the rights, integrity and confidentiality of trial subjects. It is very important to understand the background of the formation of the ICH-GCP guidelines as this, in it...

Alex McMahon and colleagues critique the International Conference on Harmonisation (ICH) guidance on good clinical practice (GCP), arguing that it is having a disastrous effect on noncommerical randomized clinical trials in Europe.

The fallacy of the popular concept that "it's good enough for clinical purposes" is becoming more widely recognized as the potentialities of scientific methods in diagnosis and therapy increase. Such a manual as this should aim to raise the dignity and improve the quality of clinical chemistry and clinical chemists, not, by conceding to prevailing opinion, perpetuate its present mediocre estate...

1 Ethno Medicines of Kolli Hills at Namakkal District in Tamilnadu and its significance in Indian Systems of Medicine G.Arunachalam, M.Karunanithi N.Subramanian, V.Ravichandran and S.Selvamuthukumar PGP College of Pharmaceutical Science and Research Institute, NH -7, Namakkal Karur Main Road, Namakkal – 637297, Tamilnadu, India. Department of CARISM, SASTRA University, Thanjavur 613402, Tamilna...

The design of a complex regulator often includes the making of a model of the system to be regulated. The making of such a model has hitherto been regarded as optional, as merely one of many possible ways. m this paper a theorem is presented which shows, under very broad conditions, that any regulator that is maximally both successful and simple must be isomorphic with the system being regulate...