Abstracts: nanoparticles. All the extracts were used separately for the synthesis of gold nanoparticles through the reduction ofaqueous AuClgold ions to gold nanoparticles. The ethanol extract of black tea and its tannin free ethanol extract produced goldnanoparticles in the size ranges of 2.5-27.5 nm and 1.25-17.5 nm with an average size of 10 nm and 3 nm, respectively.The prepared colloid gol...

Acoustic cavitation which occurs at high intensities of ultrasound waves can be fatal for tumor cells. The existence of dissolved gases and also the presence of nanoparticles (NPs) in a liquid, irradiated by ultrasound, decrease the acoustic cavitation onset threshold and the resulting bubbles collapse. On the other hand, due to unique capabilities and optical properties of gold nanoparticles (...

Research interests on radiosensitive property of gold nanoparticles (GNPs) are rapidly raised because of the extensively proved in vitro effectiveness and clinical necessity. However, the issue of targeted accumulation of GNPs in tumor tissues hindered the transference to in vivo applications. In this study, hybrid nano-sized cyclic Arg-Gly-Asp-conjugated GNPs (cRGD-GNPs) integrated with radioa...

Urinary tract infection (UTI) is a predominant condition in prostate cancer patients. Escherichia coli ORN178 (EC-178) is the uropathogen that causes recurrent infection by binding specifically to adhesins of prostate cancer cells (DU-145 cells). Gold nanoparticles (GNPs) have been used in biodiagnosis of pathogens. In this study, we have investigated the binding time of EC-178 to DU-145 cells,...

Recently, gold nanoparticles (GNPs) have shown promising applications in targeted drug delivery and contrast imaging. Although in vitro cytotoxicity of GNPs has been thoroughly studied, there are limited data on in vivo toxicity of GNPs. In this study, we evaluated the effects of intraperitoneally injected 10 nm and 50 nm GNPs (5 μg/animal) on the expression of proinflammatory cytokines (IL-1β,...

Introduction: Radiation therapy (RT) is the gold standard treatment for more than half of known tumors. There is increasing evidence that combining radiation therapy with a radiosensitizer can enhance the efficiency of this treatment modality. A radiosensitizer preferably enhances dose at the site of tumor and increases discrimination between tumor and normal surrounding tissue...

BACKGROUND The gold nanoparticles (GNPs) have potential applications in cancer diagnosis and therapy. In an attempt to characterise the potential toxicity or hazards of GNPs as a therapeutic or diagnostic tool, the fluorescence spectra in several rat organs in vivo were measured after intraperitoneal administration of GNPs. METHODS The experimental rats were divided into control and six group...

Light driven excitation of gold nanoparticles (GNPs) has emerged as a potential strategy to generate hot carriers for photocatalysis through excitation of localized surface plasmon resonance (LSPR). In contrast, carrier generation through excitation of interband transitions remains a less explored and underestimated pathway for photocatalytic activity. Photoinduced oxidative etching of GNPs wit...

The study of cellular processes such as organelle transport often demands particle tracking with microsecond time-resolution and nanometer spatial precision, posing significant challenges to existing tracking methods. Here, we have developed a novel strategy for two-dimensional tracking of gold nanoparticles (GNPs) with 25 mus time resolution and approximately 1.5 nm spatial precision, by using...

We have developed a simple method for the preparation of nearly mono-dispersed stable gold colloids with a fairly high concentration using a two step procedure. First we synthesize citrate capped gold nanoparticles and then exchange the citrate ions with triethyleneglycolmono-11-mercaptoundecylether (EGMUDE). This leads to the immediate precipitation and formation of composite assemblies. The g...