Background: Potency evaluation of rabies vaccine is a cheap, fast, high precision and consistent with ethical values is critical, so researchers have modified a variety of methods such as: National Institute of Health (NIH) method, Single Radial Immunodiffusion (SRID) and so on. The purpose of the present study was to replace an in vitro method consistent with medical ethics criteria instead of...

The 53-kDa glycoprotein of rabbit skeletal muscle sarcoplasmic reticulum was purified by lentil lectin affinity chromatography and preparative polyacrylamide gel electrophoresis and partially sequenced. Polyclonal and monoclonal antibodies were raised against the 53-kDa glycoprotein and found to cross-react with the 160-kDa glycoprotein. A combination of antibody and synthetic oligonucleotide s...

P-glycoprotein is a 170-kd glycosylated transmembrane protein, expressed in a variety of human cells and belonging to the adenosine triphosphate-binding cassette transporter family, whose membrane expression is functionally associated with the multidrug resistance phenotype. However, the mechanisms underlying the regulation of P-glycoprotein functions remain unclear. On the basis of some eviden...

Most antigenic peptides presented to CD8+ T cells are generated from cytosolic precursors and are translocated by TAP into the endoplasmic reticulum, where they associate with MHC class I molecules. TAP-deficient cells exhibit a limited capacity to deliver peptides from cytosolic proteins to class I molecules. One candidate for an alternative peptide transporter is P-glycoprotein, which transpo...

The search for potent oral drugs either through synthetic routes or by drug repurposing combating the dreaded covid-19 virus is still ongoing. coronavirus spike glycoprotein and several other non-structural proteins play crucial roles in replication transmission of this virus. Recent research have identified ivermectin, nafamostat, camostat as promising inhibitors SARS-CoV-2 target proteins. br...

Brassica vegetables are very important to human beings. Self-incompatibility (SI) is a common phenomenon in Brassica. Breeding by SI lines an way utilize heterosis of vegetables. It believed that the inheritance species controlled three linkage genes on S-locus, including SRK (S-locus receptor kinase), SCR cystine-rich protein)/SP11 protein 11), and SLG glycoprotein). female determinant SCR/SP1...

The SARS-CoV-2 virus has been responsible for a global pandemic which caused millions of deaths. Still, novel antiviral agents have investigated against SARS-CoV-2. In this view, molecular docking simulations could be used evaluating possible to tested in further experimental runs. Hence, the aim research was evaluate interaction dihydromyricetin DHM Spike glycoproteins pristine and its Delta O...

The demand for aquaculture is increasing, but production declining due to high feed costs and disease outbreaks. Viral hemorrhagic septicemia (VHS) a viral that seriously affects seawater freshwater fish in aquaculture, including the olive flounder (Paralichthys olivaceus), major Korea. However, very few vaccines are currently available virus (VHSV). nutrient-rich microalga Chlorella vulgaris h...