نتایج جستجو برای: glycomics
تعداد نتایج: 801 فیلتر نتایج به سال:
Toward Sensors for Biomedicine and Glycomics Emil Palecěk,*,† Jan Tkać,̌‡ Martin Bartosí̌k, Tomaś ̌ Bertoḱ,‡ Veronika Ostatna,́† and Jan Palecěk †Institute of Biophysics Academy of Science of the Czech Republic, v.v.i., Kraĺovopolska ́ 135, 612 65 Brno, Czech Republic ‡Institute of Chemistry, Slovak Academy of Sciences, Dub́ravska ́ cesta 9, 845 38 Bratislava, Slovakia Regional Centre for Applied Mole...
A large variety of glycans is intricately located on the cell surface, and the overall profile (the glycome, given the entire repertoire of glycoconjugate-associated sugars in cells and tissues) is believed to be crucial for the diverse roles of glycans, which are mediated by specific interactions that control cell-cell adhesion, immune response, microbial pathogenesis and other cellular events...
Covalent modification of surfaces with carbohydrates (glycans) is a prerequisite for a variety of glycomics-based biomedical applications, including functional biomaterials, glycoarrays, and glycan-based biosensors. The chemistry of glycan immobilization plays an essential role in the bioavailability and function of the surface bound carbohydrate moiety. However, the scarcity of analytical meth...
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