نتایج جستجو برای: glutathione peroxidase gshpx
تعداد نتایج: 63181 فیلتر نتایج به سال:
The aim of this study was to assess the effect of a combined 14-day treatment with rosuvastatin (10 mg/kg) and fluoxetine (10 mg/kg) on selected biochemical parameters of oxidative stress in the blood of rats. The activity of glutathione peroxidase (GPX), glutathione reductase (GR) and the total antioxidant status (TAS) were determined. A combined 14-day treatment with rosuvastatin and fluoxeti...
Normal bronchial epithelial cells (NBECs) are at risk for damage from inhaled and endogenous oxidative species and from epoxide metabolites of inhaled polycyclic aromatic hydrocarbons. Epidemiological and in vitro data suggest that interindividual variation in this risk may result from variation in NBEC expression of enzymes that inactivate reactive species by conjugating them to glutathione. Q...
Pigs from sows fed a diet deficient in Sc and low in vitamin E were fed a Torula yeast diet supplemented with 100 IU dl-a-tocopheryl acetate/kg of diet. Dietary treatments were levels of supplemental Se of 0, .025, .050, .075 or .100 ppm. Some death loss occurred in pigs receiving no supplemental Se at approximately 5 wk of age. Autopsy revealed liver and heart lesions typical of vitamin E-Se d...
In order to evaluate the anti-mutagenic effects of the potential chemoprotective compounds selenium and (S)-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-1065), CHO AA8 cells were exposed to both compounds either individually or in combination prior to irradiation. Mutation frequency following exposure to 8 Gy was evaluated by quantitation of the mutations detected at the hprt locus of th...
Purpose: To study the effect of Clematis chinensis extract (CCE) on diabetic nephropathy in rats. Methods: Eight-week old male Wistar rats were injected with streptozotocin to induce diabetes. The effects of CCE(250 or 500 mg/kg) on renal function index, fasting blood glucose (FBG), blood fat, oxidation index, and pathological kidney changes for 3 weeks were compared to those of the positive co...
Background & Aim: The biological effects of potent oxidative agents in human body are under anti-oxidative control. Functional defects of organs may result from reactions of free radicals with the cell membrane. It is known that major targets of oxygen radicals are cell membrane lipids. Some reports indicate the role of peroxides in development of atherosclerosis. Human body tissues(eg.eryt...
This study was designed to investigate the influence of maternal aerobic exercise on lipid peroxidation levels and antioxidant enzymatic activities before and after delivery. Predelivery and 1- and 24-hour post partum blood samples were collected from 18 nulliparous healthy pregnant women who exercised regularly throughout the whole period of pregnancy and from 22 matched controls. The plasma c...
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