To evaluate the effectiveness of activated charcoal in alleviating Verrucarin J, two treated groups of 10 male albino mice were treated with a sublethal dose (0.9mg/kg body weight orally) for two weeks in combination with or without activated charcoal. Highly significant increase in plasma level of lipid peroxidation (LPO), liver disease is often clinically assessed using serum enzyme activites...

Present study examines biological effects of 2.45 GHz microwave radiation in Parkes strain mice. Forty-day-old mice were exposed to CW (continuous wave) microwave radiation (2 h/day for 30 days). Locomotor activity was recorded on running wheel for 12 days prior to microwave exposure (pre-exposure), 7 days during the first week of exposure (short-term exposure) and another 7-day spell during th...

In vitro and in vivo studies of the activity of Phaleria macrocarpa Boerl (Thymelaeaceae) leaves against the therapeutic target for hypercholesterolemia were done using the HDL receptor (SR-BI) and hypercholesterolemia-induced Sprague Dawley rats. The in vitro study showed that the active fraction (CF6) obtained from the ethyl acetate extract (EMD) and its component 2',6',4-trihydroxy-4'-methox...

PurposeOur purpose was to better understand the pathogenesis of seizures associated with angiocentric glioma. Angiocentric glioma is an indolent and rare low-grade Its typical clinical presentation epileptic seizures. The tumor-associated poorly understood. Among possible pathomechanisms, increased neurotoxic concentrations glutamate has been proposed. Glutamate transporters, pyruvate carboxyla...

Objective: The present study was carried out to evaluate the anticancer property of ethanol extract of Scaevola taccada leaves against Ehrlich ascites carcinoma in Swiss albino mice. Materials and Methods: The leaves powder was subjected to continuous hot extraction using ethanol and cold maceration by water to get Ethanol and Aqueous extracts, respectively. Identification of the chemical const...

INTRODUCTION Roots of Ixora coccinea (Rubiaceae), and Rhinacanthus nasuta (Acanthaceae) and whole plants of Spilanthes ciliata (Asteraceae) are extensively used by tribal communities in South India to treat liver diseases. However, the veracity of these tribal claims has not been investigated scientifically using the liver toxin, aflatoxin. This study reports on the protective effects of these ...

SCOPE SlimTrym® is a formulated product composed of citrus polymethoxyflavones (PMFs), green tea extract, and lychee extract. We investigated the effect of dietary SlimTrym® on diet-induced obesity and associated non-alcoholic fatty liver disease (NAFLD) in mice. METHODS AND RESULTS Male C57BL/6 mice were fed a normal diet (ND), high fat diet (HFD) or HFD containing 0.1% or 0.5% SlimTrym® for...

The effect of repeated administration of aqueous extract of Enantia chloranta stem bark on selected enzyme activities of rat liver was investigated. The aqueous extract of the plant was administered to white albino rats daily at 24hr interval at a dosage level of 100mg/kg body weight after which the rats were sacrificed after receiving 1, 3 and 5 daily oral doses. Administration of the extract ...

To evaluate the chemopreventive potential of quercetin in an experimental skin carcinogenesis mouse model. Skin tumor was induced by topical application of 7, 12-dimethyl Benz (a) anthracene (DMBA) and Croton oil in Swiss albino mouse. Quercetin was orally administered at a concentration of 200 mg/kg and 400 mg/kg body weight daily for 16 weeks in mouse to evaluate chemopreventive potential. Sk...

To examine the effects of N nutrition upon endosperm development, maize (Zea mays) kernels were grown in vitro with either 0, 3.6, 7.1, 14.3, or 35.7 millimolar N. Kernels were harvested at 20 days after pollination for determination of enzyme activities and again at maturity for quantification of storage products and electrophoretic separation of zeins. Endosperm dry weight, starch, zein-N, an...