The present study was designed to investigate the effects of sleep disturbance on histological features and evaluates expression StAR protein in cortex adrenal gland adult male rats. suprarenal glands are endocrine organs that directly affected by deprivation. Sleep is a stress factor affecting steroidogenesis since it regulated hypothalamic-pituitary axis (HPA). Its hormones cholesterol-derive...

OBJECTIVES To determine the accuracy of area based Townsend Deprivation Scores (TDSs) as proxies for individual level deprivation and to compare the ability of TDSs and individual level measures of deprivation to predict selfreported health. METHODS Using data from a self completed health and behaviour survey sent to a random sample of households in Newcastle upon Tyne, UK, the ability of TDS...

Background & Aims: Change in visual experience impairs circadian rhythms. In this study, The effects of visual deprivation during critical period of brain development and melatonin intake on synaptic plasticity of hippocampal CA1 neurons were evaluated. Methods: This experimental study was done on male rats kept in standard 12 hour light/dark condition (L...

Abstract Introduction Sleep deprivation impairs some higher-order cognitive processes, but it is unclear if this reflects impaired ability to perform complex tasks, a reduction in motivation, or both. There evidence that reward motivation attenuates the effect of sleep on lower-level namely vigilant attention. We investigated extent which would mitigate placekeeping, process plays central role ...

Abstract Introduction Sleep deprivation impairs some higher-order cognitive processes, but this impairment may reflect changes in motivation as well the capacity to perform task, which has implications for intervention strategies. Here, we asked whether reward could offset effects of sleep on placekeeping, a process that is prevalent performance everyday tasks. To conduct study under pandemic c...

Effects of sleep deprivation on neural cardiovascular control may have important clinical implications. We tested the hypothesis that sleep deprivation increases heart rate, blood pressure, and sympathetic activity and potentiates their responses to stressful stimuli. We studied 8 healthy subjects (aged 40+/-5 years, 6 men and 2 women). Blood pressure, heart rate, forearm vascular resistance, a...

Deprivation indices have been widely used to evaluate neighborhood socioeconomic status and therefore examine individuals within their regional context. Although some studies on the development of deprivation indices were conducted in Korea, additional research is needed to construct a more valid and reliable deprivation index. Therefore, a new deprivation index, named the K index, was construc...

Dormant cancer cells are deprivation-resistant, and cause a number of problems for therapeutic approaches for cancers. Renal cell carcinomas (RCCs) include deprivation-resistant cells that are resistant to various treatments. In this study, the specific characteristics of deprivation-resistant cells were transcriptionally identified by next generation sequencing. The hypoxia-inducible factors (...

Prospective research indicates sleep deprivation potentiates anxiety development, yet relatively little research has examined the effects of sleep deprivation in terms of specific types of anxiety. The current study tested the association between acute sleep deprivation and panic-relevant biological challenge responding among nonclinical participants. One hundred and two participants were rando...

BACKGROUND There is little empirical evidence in support of a relationship between rates of influenza infection and level of material deprivation (i.e., lack of access to goods and services) and social deprivation (i.e. lack of social cohesion and support). METHOD Using validated population-level indices of material and social deprivation and medical billing claims for outpatient clinic and e...