introduction: several studies have evaluated the association of admission blood glucose levels and short and long term mortality after myocardial infarction and have had different results. the aim of this study was evaluation of association between admission blood glucose levels and in-hospital and one year mortality in non-diabetic patients with ami. methods: in this study, demographic, clinic...

Background: We investigated the effects of Withania somnifera root (WS) on insulin resistance, tumor necrosis factor α (TNF-α), and interleukin-6 (IL-6) in fructose-fed rats. Methods: Forty-eight Wistar-Albino male rats were randomly divided into four groups (n=12); Group I as control, Group II as sham-treated with WS by 62.5mg/g per diet, Group III fructose-fed rats received 10%...

Background: Data shows vanadium protects pancreatic beta cells (BC) from diabetic animals. Whether this effect is direct or through the relief of glucose toxicity is not clear. This study evaluated the potential effect of oral vanadyl sulfate (vanadium) on glycemic status and pancreatic BC of normal and diabetic rats. Methods: Rats were divided into five groups of normal and diabetic. Diabetes ...

Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets post-gestational hyperglycemia. To prevent these complications, we implemented preemptive supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted optimal blood glucose control pregnancies, preservation graft f...

Possessing putative hypolipidemic effects, Teucrium polium (TP) have been traditionally used as a medicinal plant in Iran. The aim of the present study was to investigate this effect on the sucrose-induced insulin resistance male rat model. Thirty Wistar male rats weighting 180 ± 20 g were divided into five groups of six each. Four groups were given sucrose 50% in drinking water for 10 weeks. I...

Abstract Objective: Insulin resistance and hyperinsulinemia are common among the women with polycystic ovarian syndrome (PCOS). Familial aggregation of PCOS has implications on the role of heredity in this disease. The aim of this study was to evaluate insulin resistance among the fathers, mothers, and siblings of the women with PCOS referring to the clinics affiliated to Shiraz University of ...

Background and aim: Acanthosis nigricans (AN) is characterized by hyperpigmented velvety plaques of body folds and neck. Insulin can have a role in the pathogenesis of this disease and hyperinsulinemia as a consequence of insulin resistance may stimulate the formation of the characteristic plaques of AN. In this study insulin resistance was compared in obese women with and without AN.</sp...

background and aims: artichoke (cynara scolymus l.) is a plant of the asteraceae family. this plant is used in herbal medicine. this study was conducted to evaluate the effect of artichokeextract on insulin, glucagon, glucose, alkaline phosphatase (alp), alanine amino transferase (alt) and aspartate amino transferase (ast) in streptozotocin-induced diabetic rats. methods: in this experimental s...

Diabetes mellitus is the most common metabolic diseases. It is estimated that its worldwide prevalence will reach to 21% up to 2050. In Iran the prevalence of diabetes is estimated to be about 14%. It divided in two categories: type 1 and type 2. Diabetes type 1 is due to absolute deficiency of insulin secretion, and type 2 characterised by resistances to insulin and its inadequate compensation...