OBJECTIVES Blast explosions are the most frequent mechanism of traumatic brain injury (TBI) in recent wars, but little is known about their long-term effects. METHODS Functional connectivity (FC) was measured in 17 veterans an average of 5.46 years after their most serious blast related TBI, and in 15 demographically similar veterans without TBI or blast exposure. Subcortical FC was measured ...

Academic researchers in the Nordic countries participate in many common projects that process large amounts of data. To function effectively, such collaborations need a grid computing infrastructure that works across a wide area and uses distributed resources efficiently. Initial evaluations of existing grid solutions, however, showed that they failed to meet this requirement. The Globus Toolki...

This paper presents our research on applying our dependability assessment method to an OGSA compliant middleware product. Our initial proof of concept experiment was implemented using a stateless Tomcat web server and Apache SOAP. This research adapts and enhances our existing fault injection software (OGSA-FIT) from the stateless environment of a standard web service to the stateful environmen...

Substance P is an important neurotransmitter or neuromodulator in central nervous system. Morphological studies have revealed the existence of substance P and its high affinity receptor, neurokinin-1 receptor, in globus pallidus. The expression of neurokinin-1 receptor in external globus pallidus has been reported to be decreased or unchanged in parkinsonian patients. To further investigate the...

BACKGROUND & AIMS Ablation of gastric inlet patches (GIP) in the cervical esophagus by argon plasma coagulation (APC) can alleviate chronic globus sensations in the throat. We investigated the efficacy of this therapy in a randomized, controlled multicenter trial. METHODS Patients with chronic globus sensations and GIP were randomly assigned 1:1 to groups that were treated with APC or a sham ...

In this paper we describe the execution model supported by suma/g, a middleware built on top of Globus for execution of Java applications on the grid. This execution model allows a user to launch Java applications that will run on a grid from her machine without requiring this machine to be part of the grid (e.g. a gLite User Interface). Additionally, it allows grid users to regard local file s...

A decade ago it was theorized that if enough parallel processing power was thrown at an I/O problem, the bottleneck would shift towards the NIC’s link speed [1]. However, today NUMA architecture changes this paradigm, it also matters on which cores these threads are located and how they are managed [2]. Transport protocols are also critical in high latency networks, TCP’s congestion control alg...

High-frequency deep brain stimulation targeting the output nucleus of the basal ganglia, the globus pallidus internus, has been suggested as a treatment modality for intractable Tourette syndrome and basal-ganglia-mediated motor tics. Recent studies on the modeling of motor tics induced by focal injections of bicuculline to the striatum, a putative model of Tourette syndrome, have shown that ti...

Neuropeptide immunohistochemistry was used to test several hypotheses of the anatomical bases of chorea and rigidity-kinesia. To test the hypothesis that elevated concentration of striatal somatostatin causes chorea, we visually compared the density of striatal neurons containing somatostatin and neuropeptide Y in brains affected by choreic or rigid-kinetic Huntington's disease (HD). The densit...

Introduction: Parkinson'sdisease isassociated withirondeposition in the brain. The T2-weighted imaging, T2* mapping, R2 mapping and Quantitative Susceptibility Mapping (QSM) are three common methods to evaluating the iron deposition in brain. Among three methods the QSM is more sensitive than others. Few studies have been used QSM for evaluating the iron deposition in the basa...