AIMS (I) To examine whether small holes produced by 248 nm excimer laser ablation in a polymer substrate could consistently produce a pressure drop in the desired target range (5-15 mm Hg) at physiological aqueous flow rates for use as an internal flow restrictor in a glaucoma drainage device, and (ii) to investigate whether external leakage could be reduced in comparison with conventional tube...

Glaucoma is the second leading cause of blindness with ∼70 million people worldwide who are blind from this disease. The currently practiced trabeculectomy surgery, the gold standard treatment used to stop the progression of vision loss, is rather draconian, traumatic to the patient and requires much surgical skill to perform. This article summarizes the more than 10-year development path of a ...

PURPOSE To report on the efficacy and safety of combined phacoemulsification and an Ahmed valve glaucoma drainage implant with respect to visual acuity improvement, intraocular pressure (IOP) control, and requirement for antiglaucoma medication. METHODS A retrospective chart review was conducted of 41 eyes (31 patients) with coexisting visually significant cataracts and uncontrolled glaucoma ...

BACKGROUND The aim of this study was to investigate the antiscarring effects of pirfenidone on foreign body reaction in a rabbit model of glaucoma drainage implant surgery. METHODS Adult New Zealand White rabbits had glaucoma drainage device implantation using Model FP8 Ahmed glaucoma valves. One eye was randomly assigned to receive postoperative intrableb injection of pirfenidone followed by...

Repositioning a glaucoma drainage device tube from the anterior chamber to the ciliary sulcus or pars plana can be a challenging procedure owing to the difficulty in obtaining tight closure of the original limbal fistula. Failure to achieve watertight and airtight closure of the fistula can result in substantial difficulty in completing other key portions of the surgery and may lead to postoper...

BACKGROUND Choroidal detachment (CD) is often observed at an early period particularly after trabeculectomy and glaucoma drainage implant surgery. However, topical antiglaucoma eye drop-induced CD is a rare complication. Here, we report a case of topical bimatoprost-induced late-onset CD after trabeculectomy and review the literature. CASE REPORT A 74-year-old man who suffered from primary op...

Introduction Anti-glaucoma medicines, laser surgery and incisional surgery all seek to lower the intraocular pressure (IOP). Incisional surgery is indicated when medical treatment and/or laser surgery have failed, are likely to fail or are not available or practical. The most standard surgical procedure is trabeculectomy (or some variation thereof e.g. ExPRESS shunt): aqueous is shunted from th...

OBJECTIVES To report the incidence and identify risk factors of postoperative complications after Baerveldt glaucoma drainage implantation. METHODS A retrospective review of the medical records of all patients at the Bascom Palmer Eye Institute, Miami, Fla, who underwent placement of a Baerveldt glaucoma drainage implant from October 1, 1992, through October 31, 1996, to determine demographic...

corticosteroids are often used as anti-inflammatory agents in a variety of inflam¬matory diseases. it is well established that long-term administration of corticosteroids predisposed the patients to develop glaucoma. although the exact pathophysiology of steroid-induced glaucoma is unknown, it is assumed that matrix metalloproteinases (mmps) have a role in its pathogenesis. to study and estimat...