Genetic studies on METH abuse and METH psychosis are influential in the fields of comorbidity of substance abuse, etiological models of schizophrenia, and the nosology of prolonged or chronic substance-induced psychosis. Most data of genetic markers associated with METH abuse or METH psychosis derived from Asian samples. Previous studies on Meth abuse and Meth psychosis have identified many pot...

The weaver mutation impairs migration of the cerebellar granular neurons and induces neuronal death during the first two weeks of postnatal life. To elucidate the molecular mechanisms for the impaired neuronal migration, we investigated the rescue mechanisms of the weaver (wv/wv) granule neurons in vitro. We found that Fab2 fragments of antibodies against a neurite outgrowth domain of the B2 ch...

Metabotropic glutamate receptors (mGluRs) control intracellular signaling cascades through activation of G proteins. The inwardly rectifying K 1 channel, GIRK, is activated by the bg subunits of G i proteins and is widely expressed in the brain. We investigated whether an interaction between mGluRs and GIRK is possible, using Xenopus oocytes expressing mGluRs and a cardiac/brain subunit of GIRK...

Despite indirect evidence of long-term survival of fetal midbrain dopamine cell suspensions in people with Parkinson’s disease1, the question remains whether grafted neurons are affected by pathogenic factors intrinsic to the parkinsonian brain. Prominent neuropathological features of Parkinson’s disease include dopaminergic neuron loss in the substantia nigra, the presence of dystrophic neurit...

s | 33 Group 2 included 112 patients who underwent open gastrectomy or open colectomy and postoperative continuous epidural analgesia. In both groups, patients with chronic pain or severe systemic disease, patients who took any analgesics, psychotherapeutic drugs, anti-anxiety drugs, or anticonvulsants were excluded. There was no difference in age, body height or weight between patients with o...

s | 33 Group 2 included 112 patients who underwent open gastrectomy or open colectomy and postoperative continuous epidural analgesia. In both groups, patients with chronic pain or severe systemic disease, patients who took any analgesics, psychotherapeutic drugs, anti-anxiety drugs, or anticonvulsants were excluded. There was no difference in age, body height or weight between patients with o...

s from the 12th meeting of the International Society for Neural Transplantation and Restoration NeuroReport 2014, 25:139–163 Note from the Publisher The following abstracts section presents abstracts from all presenters at the 12th meeting of the International Society for Neural Transplantation and Restoration. They were meant to be included in last year’s December issue of NeuroReport, but unf...