Ginkgo biloba is a widely used herbal product that could potentially have a severe interaction with warfarin, which is the most frequently prescribed anticoagulant agent in North America. Literature, however, provides conflicting evidence on the presence and severity of the interaction. In this study, we developed text processing methods to extract the ginkgo usage and combined it with prescrip...

OBJECTIVE To determine whether Ginkgo biloba is effective in treating tinnitus. DESIGN Double blind, placebo controlled trial using postal questionnaires. PARTICIPANTS 1121 healthy people aged between 18 and 70 years with tinnitus that was comparatively stable; 978 participants were matched (489 pairs). INTERVENTION 12 weeks' treatment with either 50 mg Ginkgo biloba extract LI 1370 three...

The aim of the present work was to improve and validate the HPLC-CUPRAC postcolumn method for the evaluation of active antioxidant markers from the acetonic extracts of Ginkgo biloba leaves. Improvement of the HPLC online assay was performed by evaluating the suitable loop temperature, the reaction loop length, and the impact of flow rate. Separation of the analytes was performed by the HPLC me...

BACKGROUND DNA-based testing has been gaining acceptance as a tool for authentication of a wide range of food products; however, its applicability for testing of herbal supplements remains contentious. METHODS We utilized Sanger and Next-Generation Sequencing (NGS) for taxonomic authentication of fifteen herbal supplements representing three different producers from five medicinal plants: Ech...

BACKGROUND European Regulation 1924/2006 states that all health claims made on foods need to be substantiated scientifically. OBJECTIVE To apply the PASSCLAIM criteria for the scientific substantiation of health claims on foods to herbal supplements containing Ginkgo biloba. Evaluation of three selected claimed health effects for G. biloba (improvement of blood circulation, improvement of sym...

Ginkgo biloba, a dioecious plant known as a living fossil, is an ancient gymnosperm that stands distinct from other gymnosperms and angiosperms. Ginkgo biloba var. epiphylla (G. biloba var. epiphylla), with ovules borne on the leaf blade, is an unusual germplasm derived from G. biloba. MicroRNAs (miRNAs) are post-transcriptional gene regulators that play critical roles in diverse biological and...

Soil carbon (C) in three Ginkgo (Ginkgo biloba L.) agroforestry systems, afforestation (Ginkgo alone; G), and an agricultural cropping system were compared over a five-year period. The agroforestry systems were Ginkgo + Wheat (Triticum aestivum L.) + Peanut (Arachis hypogaea L.; GWP); Ginkgo + Mulberry (Morus alba L.; GM); and Ginkgo + Rapa (Brassica napus L.) + Peanut (GRP). The agricultural s...

The final size of plant leaves is strictly controlled by environmental and genetic factors, which coordinate cell expansion cycle activity in space time; however, the regulatory mechanisms leaf growth are still poorly understood. Ginkgo biloba a dioecious species native to China with medicinally phylogenetically important characteristics, its fan-shaped unique gymnosperms, while mechanism G. de...