Chronic periodontitis is a multifactorial disease characterized by the presence of dysbiotic microbial communities that, together with genetic and environmental factors, results in chronic inflammation of the periodontium, which ultimately may trigger alveolar bone resorption (1). The reported associations between periodontal disease and other chronic disorders, including metabolic, cardiovascu...

INTRODUCTION Crown materials used in fixed prosthodontics come into close and prolonged contact with the gingiva. OBJECTIVE The purpose of this study was to evaluate the effect of different crown materials on the interleukin-one beta (IL-1β) content of the gingival crevicular fluid and to study which crown material causes the highest inflammation on the marginal gingiva on a biochemical basis...

Introduction: An acquired diastema may be a warning sign signaling advanced periodontitis. Gingival inflammation, reduced bony support, and tooth mobility contribute to the drifting of teeth, condition called pathologic migration, formed gap or space between two teeth more. Identification causative factors involved in migration is crucial for successful treatment. Case Management: 1 - A 38-year...

OBJECTIVE To review the literature concerning cetylpyridinium chloride (CPC) containing mouth rinses as effective adjuncts to toothbrushing in the prevention of plaque accumulation and gingival inflammation. MATERIALS AND METHODS Medline and the Cochrane Central Register of Controlled Trials were searched up to January 2008 to identify appropriate studies. The primary outcome measurements wer...

BACKGROUND AND OBJECTIVE A low-grade systemic inflammatory status originating from periodontal infection has been proposed to explain the association between periodontal disease and systemic conditions, including adverse obstetric outcomes. The aim of this study was to evaluate the effect of periodontal therapy during pregnancy on the gingival crevicular fluid and serum levels of six cytokines ...

Subgingival margins are often required for biologic, mechanical, or esthetic reasons. Several investigations have demonstrated that their use is associated with adverse periodontal reactions, such as inflammation or recession. The purpose of this prospective randomized clinical study was to determine if two different subgingival margin designs influence the periodontal parameters and patient pe...

We examined the effect of catechin diet on gingivitis in cats. Gingival inflammation, oral malodor, and percentage of Porphyromonas were decreased after feeding of diet with catechin compounds. We suggest that feline gingivitis can be controlled by phytomedical activities of catechin in pet food. Twenty nine cats affected with gingivitis were fed either a catechin diet of 0.8 mg/g or 0.4 mg/g o...

Humans develop periodontitis in response to challenge by microbial dental plaque. Inflammation begins after perturbation of gingival epithelial cells by subgingival bacteria interacting through pattern-recognition receptors, including the Toll-like receptors (TLR). Porphyromonas gingivalis is a major periodontopathogen that interacts with epithelial cells through its cell surface fimbriae (FimA...