Enteric glia are important components of the enteric nervous system (ENS) and also form an extensive network in the mucosa of the gastrointestinal (GI) tract. Initially regarded as passive support cells, it is now clear that they are actively involved as cellular integrators in the control of motility and epithelial barrier function. Enteric glia form a cellular and molecular bridge between ent...

1. Apply an understanding of the pathophysiology and risk factors for upper gastrointestinal (GI) bleeding to patient care. 2. Evaluate the most recent guidelines for management and prevention of upper GI bleeding. 3. Devise a plan to effectively manage acute GI bleeding and optimize treatment responses in the individual patient. 4. Design plans for the prevention of upper GI bleeding caused by...

Intestinal gases are the expression of metabolic activity of gut microbiota in the gut, particularly carbohydrates in the case of H2, CH4. Alterations in composition of gases and air handling, directly or upon challenge with food are relevant for GI and extra-GI diseases. Assessing gas composition in breath can be a very useful tool for clinic, but technical issues are crucial (breath sampling,...

M. Sawkat Anwer Anwer, DMVH, PhD, Distinguished Professor of Biomedical Sciences and Associate Dean for Research at the Cummings School of Veterinary Medicine at Tufts University. Dr Anwer has been performing GI research for more than 40 years and is the former chair of the National Institute of Diabetes and Digestive and Kidney Diseases Hepatobiliary Pathophysiology study section. As part of t...

Symptomatic involvement of the gastrointestinal (GI) tract as a prominent symptom in Langerhans' cell histiocytosis (LCH) is uncommon, occurring in less than 1 to 5% of all cases, even when the disease is in its disseminated form. Up to now, there have been reports of 18 cases of LCH with GI manifestations, including our 2 cases, with diarrhea (77.7%), protein-losing enteropathy (33.3%) and blo...

Oral vaccination enables pain-free and self-administrable vaccine delivery for rapid mass during pandemic outbreaks. Furthermore, it elicits systemic mucosal immune responses. This protects against infection at surfaces, which may further enhance protection minimize the spread of disease. The gastrointestinal (GI) tract presents a number prospective inductive sites targeting, including oral cav...

Intestinal intussusception rarely occurs in the adult population and accounts only for 1% to 5% of all the causes of intestinal obstruction. This complication is more frequent in the small bowel and can be due to different aetiologies, including inflammatory, infectious or neoplastic diseases. Malignancies account for 50% to 60% of all cases of colon invagination. The gastrointestinal (GI) trac...

Aim: To investigate upper GI bleeding as a particular complication in chronic kidney disease patients. Material and methhod: 30 chronic kidney disease patients admitted to the Nephrology Department for upper gastrointestinal bleeding over a period of 5 years. Results: 16 patients were undergoing hemodialysis (53.3%) and 14 patients were not in a hemodialysis program. There were no patients unde...

Background: Diabetes mellitus is a chronic metabolic disorder caused by an altered metabolism of carbohydrates, proteins and fats,characterised high levels glucose in the bloodstream. The present study was conducted to assess periodontal health youngpatients with type 1 diabetes mellitus.Materials & Methods: 58 patients I (Group I) both genders equal number healthy controls (group II) weree...

Background: Random induced mutation by gamma radiation is one of the genetic manipulation strategies to improve the antagonistic ability of biocontrol agents. Objectives: This study aimed to induce mutants with more sporulation, colonization rate leading to enhanced antagonistic ability (in vitro assay) comparing to wild type (WT) and the assessment of genetic differences (in situ evaluat...