Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission of the parasite to the fetus. This study was conducted to test the utility of PCR assay to detect recent infections with Toxoplasma in aborted women at various gestational ages who referred to Obstetrics and Gynecology Department of Alavi Hospital in Ardabil during 2014 and 2...

AIMS To study the localisation of the endothelial nitric oxide synthase (eNOS) in the normal placenta, with special emphasis on the implantation site in the first trimester of pregnancy, and in the different subtypes of trophoblastic cells in gestational trophoblastic disease. METHODS The immunoperoxidase technique with an antibody directed against eNOS was applied to paraffin sections from f...

BACKGROUND Gestational trophoblastic neoplasia (GTN) is a malignant disease which occurs in women of reproductive age. Treatment of GTN has an excellent outcome and further pregnancies can be expected. However, data concerning quality of life in these cancer survivor patients are limited. This study aimed to assess quality of life in women who were diagnosed with GTN and remission after treatme...

Partial or complete mole affects one in 1000  pregnancies.Partial mole is a rare form of ectopic pregnancy. There was a married woman,gravid 4,parity 1,abortion 1,and she had past medical history 0f right ectopic pregnancy.she had left ectopic pregnancy and was treated by laparascopic left salpyngectomy after failure of intramascular methotrexate treatment.After surgery  the pathology exam show...

Transformations are a common technique used to linearize data so that simple linear regression can be applied. A common transformation used is the logarithmic transformation. This transforms data that follows an exponential pattern so that a straight line can be fit to it. In this study human chorionic gonadotropin (hCG) levels in women with gestational trophoblastic disease (GTD), which are kn...

OBJECTIVE To evaluate the reproducibility of placental volume using three-dimensional ultrasound. METHODS The VOCAL (Virtual Organ Computer-aided AnaLysis) technique involves rotating an image of an object along an established axis using predefined angles. This provides a number of sections to measure manually, resulting in the object being displayed with an estimated placental volume. Four p...

http://dx.doi.org/10.1016/j.ebiom.2016.01.013 2352-3964/Crown Copyright © 2016 Published by Elsevie Gestational trophoblastic diseases (GTD) are a group of disorders that originate from the trophoblast, which is the outer layer of the blastocyst that normally gives rise to the placenta and is the first tissue to differentiate from the developing embryos after implantation. The human chorionic g...

Choriocarcinoma is a curable malignancy that occurred approximately 50% after term pregnancies, and prognosis in this form of gestational trophoblastic Disease (GTD) is Poor. The earliest onset choriocarcinoma after term pregnancy in one study was reported 3 weeks after delivery, but in current study, choriocarcinoma was diagnosed 2 weeks after delivery. 28 years-old women gravidity 2, parity 2...

Choriocarcinoma (CC) is a malignant tumor of trophoblastic tissue composed cytotrophoblastic, intermediate and syncytiotrophoblast cells. predominantly has gestational origin. The non-gestational type said to arise from the gonads pluripotent germ It rapidly invasive metastasizes widely, but it good response chemotherapy once identified. Metastatic choriocarcinoma are extremely rare in breast. ...

Thirteen patients with methotrexate-resistant metastatic trophoblastic disease have been treated with actinomycin D. Complete remissions were observed in six patients, and substantial response was noted in all but two cases. On the basis of these data, actinomycin D appears to be useful in the treatment of patients with per sistent metastatic trophoblastic disease following development of resis...