BACKGROUND Intraventricular hemorrhage (IVH) is the most common brain injury among premature infants. Neonates with IVH are at greater risk of impaired neurodevelopmental outcomes, compared with those without IVH. IVH causes destruction of the germinal matrix and glial precursor cells, with possible effects on cortical development. OBJECTIVE To investigate cortical development after uncomplic...

BACKGROUND AND PURPOSE This review focuses on the emerging principles of intracerebral hemorrhage (ICH) management, emphasizing the natural history and treatment of intraventricular hemorrhage. The translational and clinical findings from recent randomized clinical trials are defined and discussed. Summary of Review- Brain hemorrhage is the most severe of the major stroke subtypes. Extension of...

BACKGROUND AND PURPOSE Intraventricular extension of hemorrhage is a predictor of poor outcome in intracerebral hemorrhage, and iron overload contributes to brain injury after intracerebral hemorrhage. The current study investigated the role of iron in ventricular dilatation and neuronal death in a rat model of intraventricular hemorrhage (IVH). METHODS There were 2 parts in this study. First...

We reported a case report of 50-year-old woman with stroke hemorrhage due to subarachnoid hypertensive urgency, left ventricular hypertrophy, and dyslipidemia. Subarachnoid indicates the presence blood in space between pia mater arachnoid which usually results from ruptured cerebral aneurysm or arteriovenous malformation. The patient presents decreased consciousness preceded by severe headache ...

Introduction: The incidence of postneurosurgical Acinetobacter baumannii ventriculitis/meningitis, primarily due to drug-resistant strains, has increased considerably in recent years. However, limited therapeutic options are available because most antibiotics poorly penetrate the blood-brain barrier, especially pediatric patients. Case Presentation: A five-year-old boy developed ventriculitis e...

BackgroundCOL4A1/A2 variants affecting the alpha 1 and 2 chains of type IV collagen are increasingly recognized as a cause fetal neonatal intracranial hemorrhage, porencephaly, schizencephaly. Fetal magnetic resonance imaging (MRI) findings in COL4A1/A2-related disorders not well characterized.MethodsThis is retrospective case series MRI eight patients with intraparenchymal hemorrhage (IPH) COL...

We describe a case of preterm infant managed conservatively using lower threshold 25 K/uL (25 x 103/μL) for platelet transfusion. saved three extra transfusions by not the 50 (50 threshold. No complications thrombocytopenia, including petechiae, purpura, intraventricular bleeding, ecchymosis, hemorrhage, were noted following conservative approach.

BACKGROUND AND PURPOSE Several recent studies have suggested that neurosurgical procedures are not contraindicated in patients with cerebral amyloid angiopathy (CAA). The purpose of this study was to elucidate the clinical factors influencing the outcome of patients with CAA-related intracerebral hemorrhage (ICH) treated surgically. METHODS A total of 50 neurosurgical procedures (42 intracere...