venous malformations are the most common form of symptomatic vascular malformations. vm s could classify into low-flow lesions (vms) and high-flow lesions (avms). for low-flow venous lesions, direct percutaneous puncture with injection of sclerosing agents (sclerotherapy) has been described as a successful therapy. in this article, we want to introduce a patient who treated with ethanol sclerot...

Objective—The objectives of this study were to determine the role of response gene to complement 32 (RGC-32) in vascular lesion formation after experimental angioplasty and to explore the underlying mechanisms. Methods and Results—Using a rat carotid artery balloon-injury model, we documented for the first time that neointima formation was closely associated with a significantly increased expre...

OBJECTIVE To evaluate whether low-dose atorvastatin suppresses atherosclerotic lesion progression and inflammation in apolipoprotein E*3 (apoE*3)-Leiden mice beyond its cholesterol-lowering effect. METHODS AND RESULTS ApoE*3-Leiden mice were fed a high-cholesterol (HC) diet until mild atherosclerotic lesions had formed. Subsequently, HC diet feeding was continued or mice received HC supplemen...

Intersex disorders are rare congenital malformations with over 80% being diagnosed with congenital adrenal hyperplasia (CAH). It can be challenging to determine the correct gender at birth and a detailed understanding of the embryology and anatomy is crucial. The birth of a child with intersex is a true emergency situation and an immediate transfer to a medical center familiar with the diagnosi...

Severe pulmonary arterial hypertension, whether idiopathic or secondary, is characterized by structural alterations of microscopically small pulmonary arterioles. The vascular lesions in this group of pulmonary hypertensive diseases show actively proliferating endothelial cells without evidence of apoptosis. In this article, we review pathogenetic concepts of severe pulmonary arterial hypertens...

Aim. To investigate the diagnostic yield and etiologies of patients with obscure gastrointestinal bleeding (OGIB) using capsule endoscopy (CE) or double-balloon enteroscopy (DBE). Method. We studied the data of 532 consecutive patients with OGIB that were referred to Xinqiao Hospital in Chongqing from December 2005 to January 2012. A lesion that was believed to be the source of the bleeding (ul...

Dear Editor, Giant condyloma acuminate (GCA) fi rst described by Buschke, also known as Buschke-Löwenstein tumour (BLT), is a slow growing, semi malignant neoplasm of the external genitalia and perianal region that has a recurrence tendency.1 Inspite of its histologically benign appearance, BLT clinically behaves in a malignant fashion, destroying adjacent tissues, and is reported as an entity ...

SUMMARY Surgery on the head and neck region may be complicated by vascular trauma, caused by direct injury on the vascular wall. Lesions of the arteries are more dangerous than the venous one. The traumatic lesion may cause laceration of the artery wall, spasm, dissection, arteriovenous fistula, occlusion or pseudoaneurysm. We present a case of a child with a giant ICA pseudoaneurysm after tons...

Anastomosing hemangioma of the genitourinary tract is a recently described vascular lesion of the kidneys and testes. Although these lesions can occur in the renal hilum with infiltration of the hilar adipose tissue, the presence of adipocytes in this type of vascular tumor has not been reported. We described a case of an anastomosing hemangioma associated with fatty changes of the stromal comp...

The evolutionary forces responsible for the evolution of animal genitalia have a long history of controversy. Why the special interest in genitalia? In addition to the intrinsic interest of organs that are so intimately related to reproduction and fi tness, it is because of a classic property of genital evolution: the morphological forms of genitalia are often speciesspecifi c, and these forms ...