The car dispatching problem in an elevator group consists of assigning cars to the hall calls at the same time that car call are served. The problem needs to coordinate the movements of individual cars with the objective of operating efficiently the whole group. In this paper, we propose an elevator group control system based on a genetic algorithm which makes use of a novel fitness function to...

The forensic application of hereditary characteristics became possible after the discovery of human blood groups by Karl Landsteiner in 1901. The foundation for their use in kinship investigation was laid by Emil von Dungern and Ludwig Hirschfeld in 1910 by clarification of the inheritance of the ABO groups. Up to the middle of the 20th century further red cell membrane systems were discovered....

Phenotypic expression in the muscular dystrophies is variable, even with the identical mutation, providing strong evidence that genetic modifiers influence outcome. To identify genetic modifier loci, we used quantitative trait locus mapping in two differentially affected mouse strains with muscular dystrophy. Using the Sgcg model of limb girdle muscular dystrophy that lacks the dystrophin-assoc...

Tunisia has experienced a variety of human migrations that have modeled the myriad cultural groups inhabiting the area. Both Arabic and Berber-speaking populations live in Tunisia. Berbers are commonly considered as in situ descendants of peoples who settled roughly in Palaeolithic times, and posterior demographic events such as the arrival of the Neolithic, the Arab migrations, and the expulsi...

In previous papers [L.A. Foreman, J.A. Lambert, I.W. Evett, Regional genetic variation in Caucasians, Forensic Sci. Int. 95 (1998) 27-37; L.A. Foreman, Analyses to investigate appropriate measures of differentiation between European Caucasian populations using short tandem repeat (STR) data, FSS Research Report FSS-RR-804 (1999)], we have carried out detailed investigations of the level of regi...

Stratification by genetic risk factors for Alzheimer's disease (AD) may help identify groups with the greatest disease risk. Biological changes that cause late-onset AD are likely to occur years, if not decades prior to diagnosis. Here, we select a subset of the Generation Scotland: Scottish Family Health Study cohort in a likely preclinical age-range of 60-70 years (subset n = 3,495 with cogni...