نتایج جستجو برای: gene optimization

تعداد نتایج: 1450764  

Journal: :IEEE/ACM Transactions on Computational Biology and Bioinformatics 2018

2013
Vincent Gardeux René Natowicz Maria Fernanda Barbosa Wanderley Rachid Chelouah V. Gardeux R. Natowicz M. F. Barbosa

We present two methods for feature selection in high throughput transcriptomic data, in which the subsets of selected variables (the genes) are optima of a multi-objective function. In the clinical trials, the number of embedded patient cases is never higher than in the hundreds, while the number of gene expressions measured for each patient is higher than tens of thousands. These trials aim to...

Journal: :Computational biology and chemistry 2007
Shinuk Kim Junil Kim Kwang-Hyun Cho

Ordinary differential equations (ODE) have been widely used for modeling and analysis of dynamic gene networks in systems biology. In this paper, we propose an optimization method that can infer a gene regulatory network from time-series gene expression data. Specifically, the following four cases are considered: (1) reconstruction of a gene network from synthetic gene expression data with nois...

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