نتایج جستجو برای: gene expression level
تعداد نتایج: 2535376 فیلتر نتایج به سال:
Background and Objectives: Different diets have important roles in human health and aging. In the current study, we aimed to characterize the Klotho, an anti-aging protein, gene expression and protein level in the serum and assess the protein levels of Transforming growth factor-β and Platelet-derived growth factor in old rats which treated with different diets (high-fat, high-protein, low calo...
Senescence is a genetically regulated oxidative process that involves a general degradation of cellular structures and enzymes and the mobilization of the products of degradation to other parts of the plant. The cDNA-AFLP (cDNA-Amplified Fragment Length Polymorphism) analysis has been used under stringent PCR conditions afforded by ligation of adapters to restriction fragments, and the use of s...
Phenylalanine amonia-lyase (PAL) is one of the most important enzymes that plays a key role in regulationof phenylpropanoid production in plants. It catalyzes the first step of the phenylpropanoid pathway in whichL-phenylalanine is deaminated to trans-cinnamic acid. This step is significant for metabolic engineering andhyper-expression of the major phenylpropanoid, methyl chav...
Background: Radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (AVM) may be used as markers for specific vascular targeting agents. In this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...
Drought stress is one of the serious problems that restricted agronomic plant production worldwide. In molecular level, the harmful effect of drought stress is mostly caused by producing of large amount of reactive oxygen species (ROS). Catalase and Metallothionein genes have a crucial role to mope the hydrogen peroxide (H2O2) resulting reducing oxidative damage. In this research the gene expre...
Background and purpose: Chronic non-healing diabetic wounds are a major medical challenge worldwide. Stem cell therapy has been developed as a new approach in the management of such wounds that need to be explored further. In the present study we aimed to evaluate the effects of adipose derived mesenchymal stem cells (ADSCs) on gene expression level of some important inflammatory factors involv...
Background and purpose: Irreversible damage to the inner ear is known as noise-induced hearing loss (NIHL). Exposure to excessive noise can affect the expression of genes in molecules involved in development of NIHL. SLC26A4 gene or PDS is responsible for causing both syndromic and non-syndromic deafness and is located at DFNB site. The aim of this study was to investigate the expression level ...
background & aims of the study: oxidative stress increases platelet-derived growth factor (pdgf) gene expression in endothelial cells that contributes to vascular dysfunction and atherosclerosis. oxidative stress generates by dys-regulated redox balance between ros producing systems and antioxidant systems. also, curcumin (cur) as a main part of turmeric has anti- inflammatory, antioxidant, ant...
Aim and Background: micronutrients like iron as a cofactor plays an important role in the construction of a number of antioxidant enzymes. In this study the effects of salinity and iron on expression levels of ascorbate peroxidase (Cm APX) in Sistan melon Landrace were studied. Materials and Methods: three Sistan melon Landraces including Sefidak, Ghandak and Khatdar at three salinity levels ...
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