The contribution gives an overview of the LCFIVertex package, providing software tools for high-level event reconstruction at the International Linear Collider using vertexdetector information. The package was validated using a fast Monte Carlo simulation. Performance obtained with a more realistic GEANT4-based detector simulation and realistic tracking code is presented. The influence of hadro...

BACKGROUND The Monte Carlo code GEANT4 was used to implement first steps towards a treatment planning program for fast-neutron therapy at the FRM II research reactor in Garching, Germany. Depth dose curves were calculated inside a water phantom using measured primary neutron and simulated primary photon spectra and compared with depth dose curves measured earlier. The calculations were performe...

Introduction: Spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. At present, the main source of data for cellular dosimetry is the s-values provided by MIRD. However, the MIRD s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. In this study, we used Geant4-DNA...

Therapeutic irradiation with protons and ions is advantageous over radiotherapy with photons due to its favorable dose deposition. Additionally, ion beams provide a higher relative biological effectiveness than photons. For this reason, an improved treatment of deep-seated tumors is achieved and normal tissue is spared. However, small deviations from the treatment plan can have a large impact o...

PURPOSE Although the Monte Carlo (MC) method allows accurate dose calculation its usage is limited due to long computing time. In order to gain efficiency, a new macro MC (MMC) technique for proton dose calculations in homogeneous materials has been developed. METHODS The macro MC is based on a local to global MC approach. The local simulations using Geant4 consist of mono-energetic proton pe...

introduction: spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. at present, the main source of data for cellular dosimetry is the s-values provided by mird. however, the mird s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. in this study, we used geant4-dna...

Background: Hadron therapy for malignant tumor is becoming increasingly popular. There are many factors which effect on implementation of a proper treatment planning. The purpose of this work is to investigate the inhomogeneity effects as affecting factor on proton range, Full width at half maximum (FWHM) and 20% position of penumbra (P20) by MCNPX code. Materials and Methods: An inhomogeneous ...