نتایج جستجو برای: gd1

تعداد نتایج: 175  

Journal: :Glycobiology 2007
Zeljka Vukelić Svjetlana Kalanj-Bognar Martin Froesch Laura Bîndila Boris Radić Mark Allen Jasna Peter-Katalinić Alina D Zamfir

Gangliosides (GGs), involved in malignant alteration and tumor progression/invasiveness, are considered as tumor biomarkers or therapeutic targets. Here, we describe the first systematic GG composition characterization in human gliosarcoma versus normal brain tissue using our recently developed mass spectrometry (MS) methods, based on nano-electrospray (nano-ESI), Fourier-transform ion cyclotro...

2013
Aleš Hrabec Stefania PIZZINI Alexandra MOUGIN Stéphane MANGIN Mairbek CHSHIEV Fausto SIROTTI Laurent RANNO

Within the last two decades, domain wall manipulation became one of the undetachable partsof spintronics. The interaction between spin-polarized conduction electrons and localizedmagnetic moments in terms of giant magnetoresistance in 1988 and in terms of spin-transfertorque in 1996, launched an avalanche of experimental work on current-inducedmagnetization dynamics. Despite the...

2001
Marc-André Wurbel Marie Malissen Delphine Guy-Grand Eric Meffre Michel C. Nussenzweig Mireille Richelme Bernard Malissen

CC chemokine receptor (CCR) 9, the receptor for the CC-chemokine CCL25/ thymus-expressed chemokine (TECK), is mainly expressed by thymocytes and by intraepithelial (IEL) and lamina propria lymphocytes of the small intestine. To study the biologic role of CCR9, a mouse strain was generated in which the CCR9 gene was deleted. In spite of the high level of CCR9 found in doubleand singlepositive th...

2017
Pramod K Mistry Elena Lukina Hadhami Ben Turkia Suma P Shankar Hagit Baris Marwan Ghosn Atul Mehta Seymour Packman Gregory Pastores Milan Petakov Sarit Assouline Manisha Balwani Sumita Danda Evgueniy Hadjiev Andres Ortega Sebastiaan J M Gaemers Regina Tayag M Judith Peterschmitt

Eliglustat, an oral substrate reduction therapy, is a first-line treatment for adults with Gaucher disease type 1 (GD1) who are poor, intermediate, or extensive CYP2D6 metabolizers (>90% of patients). In the primary analysis of the Phase 3 ENGAGE trial (NCT00891202), eliglustat treatment for 9 months resulted in significant reductions in spleen and liver volumes and increases in hemoglobin conc...

Journal: :Journal of human evolution 2006
Andy I R Herries Justin W Adams Kevin L Kuykendall John Shaw

Speleological, paleomagnetic, mineral magnetic, and biochronological analyses have been undertaken at the Gondolin hominin-bearing paleocave, North West Province, South Africa. Two fossiliferous but stratigraphically separate sequences, GD2 and GD1/3, which were once part of a large cavern system, have been identified. Although some comparative paleomagnetic samples were taken from the GD 1, 3,...

Journal: :The Journal of biological chemistry 1984
A Basu R H Glew L B Daniels L S Clark

Glucocerebrosidase from normal human spleen, and spleen from cases of neurologic (types 2 and 3) and nonneurologic (type 1) Gaucher's disease, was delipidated and inactivated by extraction from membranes with sodium cholate and ice-cold 1-butanol. Control glucocerebrosidase was stimulated markedly by large quantities (20-30 micrograms/assay) of phosphatidylserine (PS), or by a combination of sm...

Journal: :Experimental animals 2008
Yea Eun Lee Sang Kuk Byun Sunhee Shin Ja Young Jang Byong-il Choi Dongsun Park Jeong Hee Jeon Sang-Seop Nahm Jong-Koo Kang Seock-Yeon Hwang Jong-Choon Kim Yun-Bae Kim

The present study was conducted to elucidate the susceptibility of embryos and fetuses at different gestational stages to the maternal stress in mice. Groups of pregnant ICR mice were subjected to daily 12-h restraint stress, taped in the supine position on a plastic board, on gestational days (GD) 1-4, 5-8, 9-12 and 13-16, respectively. Caesarean sections were performed on gestational day 18, ...

اخوان , محمد, شاکری پور , حمیده,

  The granular Gd1-x-zPrxCazBa2Cu3O7-δ high-temperature cuprate samples with 0.0 ≤ x ≤ 0.3 and 0.0≤ x ≤ 0.35 are prepared by standard solid state reaction and characterized by XRD and SEM techniques. The BaCuO2 and impurity phases are less than 1% in the samples having high levels of pr and Ca concentrations. The electrical resistivity measurements show a nonlinear reduction in Tc(x,z=etc) vers...

2009
Hubert Chanson

where subscripts 1 and 2 refer to the upstream and downstream flow conditions, respectively; F Froude number; F=V / gd; d and V flow depth and velocity, respectively; and g=gravity acceleration. The hydraulic jump is typically classified in terms of its inflow Froude number F1=V1 / gd1, which must be greater than unity Bélanger 1828; Henderson 1966 . For F1 slightly above unity, the hydraulic j...

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