We isolated non-O1, non-O139 Vibrio cholerae from pleural effusion in a patient with recurred advanced gastric cancer after total gastrectomy. We also recovered the organism from the patient's stool culture. The patient did not experience gastrointestinal symptoms such as diarrhea except heartburn and epigastric discomfort from stomach cancer before admission. The suspected route of infection i...

The incidence of cancer in Crohn's disease has been evaluated in 473 patients admitted to Rigshospitalet during the period 1 April 1964 to 1 January 1983. The patients' condition at the end of the survey, their survival, and the number and location of cancers were registered. During the survey period 23 cancers (4.9%) were found. Five were intestinal (1.1%) and were split evenly among the two s...

BACKGROUND Removal of the appendix might induce physiological changes in the gastrointestinal tract, and subsequently play a role in carcinogenesis. Therefore, we conducted a nationwide register-based cohort study in Sweden to investigate whether appendectomy is associated with altered risks of gastrointestinal cancers. METHODS A population-based cohort study was conducted using the Swedish n...

With the widespread application of endoscopic submucosal dissection for the treatment of gastrointestinal neoplasms, accurate determination of the invasion depth prior to intervention has become an indispensable part of treatment planning. Narrow-band imaging (NBI) is a novel endoscopic technique that may enhance the accuracy of diagnosis. Magnifying endoscopy with NBI has been shown to be effe...

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors arising from the wall of the gastrointestinal tract with immunohistochemical reactivity for CD117 antibody, and usually prevalent in the fifth to seventh decade of life. The specific practical diagnostic criteria for GIST are c-kit expression (CD117), mitotic score, and the tumour size. The stomach is the most common site of lo...

Soft tissue sarcomas (STS) are a heterogeneous group of tumors (Table 1) that account for approximately 1% of all adult cancer (Clark et al., 2005). There are more than 50 subtypes that are stratified by their histological appearance, presence or absence of characteristic gene translocations, or sensitivity to chemotherapy. They can be found in nearly any site in the body, but upper and lower e...

Introduction: Involving approximately 4% of malignancies in women, ovarian cancer remains one of the most fatal cancers. However, it is important to consider conditions which are not primary ovarian diseases, but mimic their behaviors. In the present study, the epidemiological characteristics of extra-ovarian conditions mimicking ovarian masses are evaluated. Meth...

Short-chain fatty acids (SCFAs) are physiological regulators of growth and differentiation in the gastrointestinal tract, and we have previously shown that apoptosis induced in colonic cell lines by these compounds is dependent on their metabolism by B-oxidation in the mitochondria (B. G. Heerdt et al., J. Biol. Chem., 266: 19120-19126, 1991; Cancer Res., 54: 3288-3293, 1994). Because tumors in...

Sphingolipids in digestive system are responsible for numerous important physiological and pathological processes. In the membrane of gut epithelial cells, sphingolipids provide structural integrity, regulate absorption of some nutrients, and act as receptors for many microbial antigens and their toxins. Moreover, bioactive sphingolipids such as ceramide or sphingosine-1-phosphate regulate cell...