It has been shown that small amounts of the digestive secretions normally present in the duodenum regurgitate into the stomach following operative anastomosis between the stomach and the upper intestinal tract. As the duodenal contents are alkaline in reaction this reflux is thought by many to result in a decrease in the acidity of the gastric contents. The purpose of the investigations reporte...

I)I)ISONIAN pernicious anemnia is ami expressiomi of the deficiemicy of vitan imi B12 which results from lack of secretion of Castle’s imit.rimisic factor iii the stomach. It has been kuioivn to be associated with atrophy of the gastric mucosa for about 80 yearst and with gastric achlorhydria for 70 years.2 The latter has been so constant. a fimiding that it has almost always been regarded as e...

After surgical removal of all salivary secretions ("desalivation"), rats increase their consumption of water while eating dry laboratory chow. In the present experiments, desalivated rats drank even more water while they ate "powdered" high-salt food (i.e., <15-mg food particles). The Na+ concentration of systemic plasma in these animals was not elevated during or immediately after the meal, wh...

Chronic duodenogastric reflux induces gastric adenocarcinomas in the rat without the use of carcinogens. Altogether, 186 male Wistar rats were randomised to undergo either a simple gastrojejunostomy or a gastrotomy and sacrificed at eight weekly intervals for 56 weeks. No control animals developed dysplasia or carcinoma. All rats subjected to a gastrojejunostomy showed hyperplasia of the prolif...

BACKGROUND : Helicobacter pylori is a gram-negative bacteria known as the causative agent of chronic gastritis, peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. Several studies have correlated H. in pathogenesis upper airway diseases. can be detected saliva, oropharyngeal aphthae, nasal sinus mucosa, secretions from tympanic cavities, larynx, pharyngeal tiss...

Background: Esophageal inlet patch (IP) refers to heterotopic gastric mucosa in the cervical esophagus. Secretions from IP may produce symptoms of laryngopharyngeal reflux (LPR) and accelerate progression lung disease. We aimed characterize significance among patients with advanced pulmonary disease, including transplant (LTx) recipients, assess outcomes following ablation. Methods: established...

the dorsal skin of the iranian frog, rana ridibanda, is associated with numerous prominent granular glands which extract their secretions in the response to stressor or invading pathogens .the secretions have broad spectrum antimicrobial effects. in this research the effect of antimicrobial skin secretions from iranian frog (rana ridibanda) has been examined against gram positive methycillin re...

The mammalian esophagus has the capacity to secrete a HCO(3)(-) and mucin-rich fluid in the esophageal lumen. These secretions originate from the submucosal glands (SMG) and can contribute to esophageal protection against refluxed gastric acid. The cellular mechanisms by which glandular cells achieve these secretions are largely unknown. To study this phenomenon, we used the pH-stat technique t...

The secretion of pepsin in the gastric juice of patients with peptic ulcer has been the subject of much investigation. Early work was carried out mainly on resting juices or on the aspirated products of an Ewald meal (Willcox, 1908; Boas, 1925; Hirsch-Mamroth and Rindfleisch, 1925; Polland and Bloomfield, 1930; Vanzant, Osterberg, Alvarez, and Rivers, 1933; Mullins and Flood, 1935), and appeare...