Quiz 1. What is the diagnosis? 2. Describe the characteristic patterns shown in the Gallium-67 scan (Fig. 2). 3. Skin lesions occur in 75% of patients with this condition. Is this true or false? 4. Lesions respond to treatment with corticosteroids. Is this true or false? 5. Spontaneous remissions occur in nearly two-thirds of patients, but the course is chronic or progressive in 10% to 30%. Is ...

Necrotizing otitis externa is a potentially lethal infection that starts in the external auditory canal and may progress to the skull base. It happens in elderly diabetic patients and is associated to a high morbi-mortality rate. The major causal agent is Pseudomonas aeruginosa, in 96 to 98% of the cases. The infection extends from the osteocartilaginous junction to the temporal bone by means o...

BACKGROUND The use of cardiac implantable electronic devices (CIED) is increasing, and their associated infections result in significant morbidity and mortality. The introduction of better cardiac imaging techniques could be useful for diagnosing this condition and guiding therapy. Our objective was to systematically assess the diagnostic accuracy of Fluor-18-fluorodeoxyglucose positron emissio...

Introduction: This study was launched to evaluate the sensitivity and specificity of 99mTc-Ciprofloxacin to distinguish infection foci induced by staphylococcus aureus and inflammation lesions induced by carrageenan in the rat foot in comparison with 67Ga-Citrate scintigraphy. Methods: The labeling and quality control of 99mTc-Ciprofloxacin kits have been perfo...

Gallium 67 (67Ga) lung scanning was performed in 100 consecutive cases in which because of the history, clinical data, or abnormal radiological findings, a bronchial carcinoma was suspected. This study allows the conclusion that a negative as well as a positive scan is an important element in the diagnosis of some cases of bronchial carcinoma. The method is most helpful in the preoperative diag...

Introduction Gallium-67 (67Ga) has been used as a radionuclide for imaging a variety of solid tumors since 1969. Since then use of various gallium-based radiotracers has been reported. Recently, 67Ga-labeled acetylacetate bis(thiosemicarbazones) (67Ga-AATS) complex with significant tumor accumulation and fast blood clearance has been employed. Materials and Methods In this study, the absorbed d...

Gallium is antiproliferative to many types of cancer, due primarily to its ability to act as a non-functional mimic of ferric iron (Fe(3+)). Because Fe(3+) is needed for ribonucleotide reductase activity--and thus DNA synthesis--gallium can inhibit DNA production and cell division. Diagnostic gallium scans have shown that hepatocellular carcinoma (HCC) is commonly avid for gallium. Furthermore,...