BACKGROUND T1-weighted (T1W) hyperintense nodules against a background of cirrhosis are diagnostically challenging in daily practice. All regenerative nodules, dysplastic nodules and hepatocellular carcinoma (HCC) might present hyperintense on T1W imaging (T1WI), so T1W hyperintense nodules cannot be definitively characterized as dysplastic nodules or HCC before biopsy, resection or transplanta...

PURPOSE To develop a simple tissue phantom to study the effects of various imaging parameters and gadolinium concentrations on magnetization transfer (MT) and lesion-to-background ratios. METHODS A commercial egg product was doped with gadolinium in concentrations of 0.0 to 1.0 mmol/L and cooked. The T1 and T2 values were determined for the phantom materials and for the white and gray matter ...

In the title compound, [Gd(C(8)H(6)NO(2))(3)(H(2)O)](n), the gadolinium(III) ion is coordinated by eight carboxyl-ate O atoms and one water mol-ecule. The carboxyl-ate ligands bridge pairs of gadolinium(III) ions, forming a zigzag chain along [100]. Hydrogen bonds link the chains into sheets parallel to (001).

Introduction Detection of microvascular obstruction (MO) with gadolinium first-pass perfusion (FP) and late gadolinium enhancement (LGE) MRI predicts outcomes of STEMI patients. Previous data indicate the presence of MO early after MI correlates to worse prognosis and left ventricular (LV) remodeling. Nonetheless, FP and early hypoenhancement on LGE may persist after reperfused STEMI for a vari...

Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder seen in patients with renal dysfunction, commonly precipitated by administration of gadolinium contrast. There is no consistently successful treatment, but oral steroids, topical dovonex, extracorporeal photopheresis, and plasmapheresis have been tried [http://www.icnfdr.org/ Last accessed: 1/6/2017]. Avoidance of gadolinium in such pa...

Methods Steady-state free precession (SSFP) imaging was performed to assess ventricular function, along with tagging. Black blood T1 and T2 weighted fast spin echo sequences were acquired for tissue characterisation and phase contrast imaging was used to quantify blood flow. First pass perfusion imaging was performed during the administration of gadolinium and finally Late Gadolinium Enhancemen...

patients with mitochondrial encephalopathy, lactic acidosis and stroke-like episodes (melas) present with recurrent and partially reversible neurological deficits. lesions of melas classically cause a signal change in both the grey and white matter, predominantly in the occipital and parietal lobes. these lesions mimic infarction. here, we reported a case of melas with rare neuroimaging finding...

Introduction Late gadolinium enhancement can identify focal fibrosis, but cannot evaluate diffuse myocardial fibrosis. Multiple methods have been used to determine the partition coefficient (l) and volume of distribution (Vd) of gadolinium to quantify diffuse myocardial fibrosis, including first-pass and T1 mapping based techniques. These two techniques have not been directly compared in the sa...

A new cationic gadolinium contrast agent is reported for delayed gadolinium enhanced magnetic resonance imaging of cartilage (dGEMRIC). The agent partitions into the glycosaminoglycan rich matrix of articular cartilage, based on Donnan equilibrium theory, and its use enables imaging of the human cadaveric metacarpal phalangeal joint.

The cardiovascular adaptation at the onset of voluntary static exercise is controlled by the autonomic nervous system. Two neural mechanisms are responsible for the cardiovascular adaptation: one is central command descending from higher brain centers, and the other is a muscle mechanosensitive reflex from activation of mechanoreceptors in the contracting muscles. To examine which mechanism pla...