Background Cure rates for chronic hepatitis C have improved dramatically with direct-acting antivirals (DAAs), but treatment barriers remain. We aimed to compare treatment initiation rates and barriers across both interferon-based and DAA-based eras. Methods We conducted a retrospective cohort study of all patients with chronic hepatitis C seen at an academic hepatology clinic from 1999 to 20...

repetitive episodes of brief regional ischemia have been shown to reduce the severity of life-threatening ventricular anhythrnias and infarct size that occur during prolonged occlusion of the coronary artery. this phenomenon is known as ischemic preconditioning. during studies in anesthetized, open chest wistar rats, we accidentally observed that poorly ventilated animals had a reduced severity...

‎‎The equivalence relation isoclinism partitions the class of all pairs of groups‎ ‎into families‎. ‎In this paper‎, ‎a complete classification of the set of all pairs $(G,G')$ is established‏‎,‎ whenever‎ $G$ is a $p$-group of order at most $p^5‎‏$‎ and ‎$p$ is a prime number greater than 3. Moreover‎, ‎the classification of pairs $(H,H')$ for extra special $p$-groups $H$ is also given.

Many wind-power facilities in the United States have established effective monitoring programs to determine turbine-caused fatality rates of birds and bats, but estimating the number of fatalities of rare species poses special difficulties. The loss of even small numbers of individuals may adversely affect fragile populations, but typically, few (if any) carcasses are observed during monitoring...

Thirty-seven patients were given a single, 2-g intravenous bolus injection of flucloxacillin prior to open-heart surgery. Within 12 h, flucloxacillin concentrations in serum and heart valves declined from 125.2 to 4.4 micrograms/ml and from 16.5 to 3.7 micrograms/g, respectively. Concentrations in subcutaneous tissue and muscle were almost identical, declining from 14.7 or 14.2 micrograms/g to ...

We observe that in many F-theory models, tuning a specific gauge group $G$ and matter content $M$ under certain circumstances leads to an automatic enhancement larger $G' \supset G$ $M' M$. propose this is true for any theory $G, M$ whenever there exists containing $G', M'$ cannot be Higgsed down give number of examples including non-Higgsable factors, nonabelian abelian exotic matter. In each ...

The dark channel prior (DCP) technique is an effective method to enhance hazy images. Dark channel is an image with the same size as the hazy image which represents the haze severity in different places of the image. The DCP method suffers from two problems: it is incapable for removing haze from smooth regions, causing blocking effects on these areas; it cannot properly reduce a haze with a no...