Abstract Better diagnostic tools are needed to combat the ongoing COVID-19 pandemic. Here, meet this urgent demand, we report a homogeneous immunoassay detect IgG antibodies against SARS-CoV-2. This serological assay, called SATiN, is based on tri-part Nanoluciferase (tNLuc) approach, in which spike protein of SARS-CoV-2 and G, fused respectively two different tNLuc tags, used as antibody probe...

objectives: the purpose of this study was to determine the functional mobility and balance in the elders after total hip arthroplasty in healthy coparison to elders. methods & materials: the current cross-sectional study was done on 20 patients (70.9±4.2) with hip osteoarthritis 6 months after total hip arthroplasty and 20 healthy subjects (73±5.7) as control group. patient group was assigned w...

background: vasopressin type 2 receptor (v2r) plays an important role in the water reabsorption in the kidney collecting ducts. v2r is a g protein coupled receptor (gpcr) and the triplet of amino acids aspartate-arginine-histidine (drh) in this receptor might significantly influence its activity similar to other gpcr. however, the role of this motif has not been fully confirmed. therefore, the ...

objective(s): the current study reports the production and biocompatibility evaluation of a ternary nanocomposite consisting of ha, pla, and gelatin for biomedical application.materials and methods: hydroxyapatite nanopowder (ha: ca10(po4)6(oh)2) was produced by burning the bovine cortical bone within the temperature range of 350-450 oc followed by heating in an oven at 800. synthesis of the te...

The potency of cellular immune responses strongly depends on T cell avidity to antigen. Yet, functional avidity measurements are rarely performed in patients, mainly due to the technical challenges of characterizing heterogeneous T cells. The mean functional T cell avidity can be determined by the IFN-γ Elispot assay, with titrated amounts of peptide. Using this assay, we developed a method rev...

background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...