OBJECTIVE The purpose of this study was to determine whether amnion-derived cellular cytokine solution (ACCS) could improve the quality of epithelialization and accelerate closure of dermatome-created partial-thickness wounds in normal and streptozotocin-induced diabetic pigs. METHODS Dermatome-created partial-thickness wounds were sealed with wound chambers in healthy and diabetic pigs and w...

OBJECTIVE This study aimed to investigate the effect of opium dependency on the healing of third-degree burns in rats. MATERIAL AND METHODS Twenty-four rats were randomly divided to experimental and control groups. In the experimental group, opium was added to the drinking water for 21 days at increasing concentrations. The control group did not receive opium. To prove dependency on opium in ...

OBJECTIVE Certain cytokines, especially those known as growth factors, have been demonstrated to mediate or modulate burn wound healing. Experimental and clinical evidence suggests that there are therapeutic advantages to the wound healing process when these agents are utilized. Positive effects have been reported for 4 types of wounds seen in the burn patient: partial-thickness wounds, full-th...

abstract background: the retroauricular-temporal or washio flap has been introduced for reconstruction of partial nose and cheek defects, and has many advantages. we decided to evaluate the extended use of this technique in order to repair full thickness nasal defects. methods: superficial temporal and retroauricular arteries are identified with doppler flowmetry. selection points a, b, c and d...

Bacterial infections, especially multidrug-resistant bacterial infections, are an increasingly serious problem in the field of wound healing. Herein, bacterial cellulose (BC) decorated by 4,6-diamino-2-pyrimidinethiol (DAPT)-modified gold nanoparticles (Au-DAPT NPs) is presented as a dressing (BC-Au-DAPT nanocomposites) for treating bacterially infected wounds. BC-Au-DAPT nanocomposites have be...

BACKGROUND An artificial dermal matrix such as Integra (Integra Life Sciences Corporation, USA) provides a wound bed template for vascular and fibrocyte ingrowth as well as collagen remodelling. Dermal repair leads to epidermal and basement membrane regeneration. Burn wounds in particular have been shown to benefit from Integra by enhanced wound healing. OBJECTIVE To evaluate the effect of fi...

objective(s): this study was aimed at investigating the synergy effects of aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. materials and methods: in order to determine the concentration of silver nanoparticles in aloe vera gel, the mbc methods were applied on the most common bacteria infecting wounds, staphylococcus aureus, escherichia coli, pseudomonas aerugin...

Impaired wound healing in diabetic patients is a serious complication that often leads to amputation or even death with limited effective treatments. Tuo-Li-Xiao-Du-San (TLXDS), a traditional Chinese medicine formula for refractory wounds, has been prescribed for nearly 400 years in China and shows good efficacy in promoting healing. In this study, we explored the effect of TLXDS on healing of ...