OBJECTIVE We show with both a clinical case and measurements using the American College of Radiology mammography phantom that some digital mammography acquisition and image display combinations lead to both marked over- and underestimation of lesion sizes on geometrically magnified images. CONCLUSION The results of this study indicate that the accuracy of lesion size measurements in all magni...

OBJECTIVE To compare the diagnostic performance of new and established full-field digital mammography (FFDM) systems. MATERIALS AND METHODS During a 15-month period, 1038 asymptomatic women who visited for mammography were prospectively included from two institutions. For women with routine two-view mammograms from established FFDM systems, bilateral mediolateral oblique (MLO) mammograms were...

BACKGROUND Mammographic percent density is an established marker of breast cancer risk. In a study of screen film mammograms, we recently reported a novel feature from the pectoral muscle region to be associated with breast cancer risk independently of area percent density (APD). We now investigate whether our novel feature is associated with risk in a study based on full-field digital mammogra...

BACKGROUND The computer-aided detection (CAD) system on mammography has the potential to assist radiologists in breast cancer screening. The purpose of this study is to evaluate the diagnostic performance of the CAD system in full-field digital mammography for detecting breast cancer when used by dedicated breast radiologist (BR) and radiology resident (RR), and to reveal who could benefit the ...

background: mammography is the primary imaging technique for detection and diagnosis of breast cancer; however, the contrast of a mammogram image is often poor, especially for dense and glandular tissues. in these cases the radiologist may miss some diagnostically important microcalcifications. in order to improve diagnosis of cancer correctly, image enhancement technology is often used to enha...

PURPOSE To compare the contrast-detail (CD) characteristics of screen-film (SF) and postprocessed digital images by using a phantom-based method. MATERIALS AND METHODS Images of a CD phantom with polymerized methyl methacrylate were acquired with SF and full-field digital mammography systems at matched exposure conditions. A four-alternative forced-choice experiment was conducted with seven o...

PURPOSE The objective of this study was to conduct a value analysis of digital breast tomosynthesis (DBT) for breast cancer screening among women enrolled in US commercial health insurance plans to assess the potential budget impact associated with the clinical benefits of DBT. METHODS An economic model was developed to estimate the system-wide financial impact of DBT as a breast cancer scree...

X-ray scatter is a major cause of nonlinearity in densitometry measurements using digital mammography. Previous scatter correction techniques have primarily used a single scatter point spread function to estimate x-ray scatter. In this study, a new algorithm to correct x-ray scatter based on image convolution was implemented using a spatially variant scatter point spread function which is energ...