نتایج جستجو برای: frequent relapses

تعداد نتایج: 132242  

2017
Joel Raffel Arie R. Gafson Samer Dahdaleh Omar Malik Brynmor Jones Richard Nicholas

BACKGROUND In people with multiple sclerosis treated with interferon-beta or glatiramer acetate, new MRI lesions and relapses during the first year of treatment predict a poor prognosis. OBJECTIVE To study this association in those receiving natalizumab. METHODS Data were collected on relapses, new MRI activity, and Modified Rio Score after initiation of natalizumab in an observational coho...

Journal: :Haematologica 2012
Virginie Gandemer Sylvie Chevret Arnaud Petit Christiane Vermylen Thierry Leblanc Gérard Michel Claudine Schmitt Odile Lejars Pascale Schneider François Demeocq Brigitte Bader-Meunier Françoise Bernaudin Yves Perel Marie-Françoise Auclerc Jean-Michel Cayuela Guy Leverger André Baruchel

BACKGROUND The prognosis of patients with relapses of ETV6/RUNX1-positive acute lymphoblastic leukemia remains to be evaluated, particularly with regards to the frequency of late relapses. We performed a long-term, follow-up retrospective study to address the outcome of patients with ETV6/RUNX1-positive leukemia relapses. DESIGN AND METHODS Among the 713 children tested for ETV6/RUNX1 enrolle...

2012
Virginie Gandemer Sylvie Chevret Arnaud Petit Christiane Vermylen Thierry Leblanc Gerard Michel Claudine Schmitt Odile Lejars Pascale Schneider Francois Demeocq Brigitte Bader-Meunier Francoise Bernaudin Yves Perel Marie-Francoise Auclerc Jean-Michel Cayuela Guy Leverger Andre Baruchel Gérard Michel François Demeocq Françoise Bernaudin Marie-Françoise Auclerc André Baruchel

Background. The prognosis of relapses of ETV6/RUNX1-positive acute lymphoblastic leukemia remains to be evaluated, particularly with regards to the frequency of late relapses. We performed a long term follow-up a retrospective study to address the outcome of ETV6/RUNX1-positive leukemia relapses. Design and Methods. Among the 713 children tested for ETV6/RUNX1 enrolled into the FRALLE 93 protoc...

2013
Antti Hakalahti Kari Ylitalo Pekka Raatikainen

Aims: Due to frequent relapses after initial ablation, there is need to develop accurate and practical preoperative means to predict atrial fibrillation (AF) ablation outcome. Methods: We evaluated the power of diastolic echocardiographic parameters in predicting the outcome of AF ablation. Forty-nine patients with symptomatic and drug-resistant paroxysmal or persistent AF, who underwent wide c...

Journal: :Blood 2013
David M Ross Susan Branford John F Seymour Anthony P Schwarer Christopher Arthur David T Yeung Phuong Dang Jarrad M Goyne Cassandra Slader Robin J Filshie Anthony K Mills Junia V Melo Deborah L White Andrew P Grigg Timothy P Hughes

Most patients with chronic myeloid leukemia (CML) treated with imatinib will relapse if treatment is withdrawn. We conducted a prospective clinical trial of imatinib withdrawal in 40 chronic-phase CML patients who had sustained undetectable minimal residual disease (UMRD) by conventional quantitative polymerase chain reaction (PCR) on imatinib for at least 2 years. Patients stopped imatinib and...

Journal: :Digestive diseases 2007
Andreas Leodolter Roberto Penagini

On-demand proton pump inhibitor (PPI) therapy is an attractive option for long-term management of gastroesophageal reflux disease (GERD). Controlled trials in non-erosive reflux disease (NERD) patients have shown sufficient symptom control in most patients with a high rate of willingness to continue treatment and substantial saving on PPI expenditure. However, due to the slow onset of action of...

Journal: :Annals of the rheumatic diseases 1993
V Kyle B L Hazleman

OBJECTIVES To examine the clinical course of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in a prospective study, after the initial two months. METHODS Seventy four patients with PMR/GCA were followed for a median of 60 weeks. Detailed clinical and laboratory records were made on each visit. RESULTS Twenty per cent of patients with PMR developed GCA and 24% of patients with G...

2010
Ritesh Agarwal Ajmal Khan Dheeraj Gupta Ashutosh N. Aggarwal Akshay K. Saxena Arunaloke Chakrabarti

BACKGROUND AND AIM Allergic bronchopulmonary aspergillosis (ABPA) is classified radiologically based on the findings of central bronchiectasis (CB) and other radiologic features (ORF). However, the long-term clinical significance of these classifications remains unknown. We hypothesized that the immunological activity and outcomes of ABPA could be predicted on HRCT chest finding of high-attenua...

2018
Juan M Pericàs Carlos Cervera Asunción Moreno Cristina Garcia-de-la-Mària Manel Almela Carles Falces Eduard Quintana Bàrbara Vidal Jaume Llopis David Fuster Carlos A Mestres Francesc Marco Jose M Miró

BACKGROUND International guidelines recommend 4 weeks of treatment with ampicillin plus gentamicin (A+G) for uncomplicated native valve Enterococcus faecalis infective endocarditis (EFIE) and 6 weeks in the remaining cases. Ampicillin plus ceftriaxone (A+C) is always recommended for at least 6w, with no available studies assessing its suitability for 4w. We aimed to investigate differences in t...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2006
A J M Ferreri E Viale M Guidoboni A Giordano Resti C De Conciliis L Politi A A Lettini F Sacchetti R Dolcetti C Doglioni M Ponzoni

BACKGROUND A pathogenic link between hepatitis C virus (HCV) and MALT-type lymphomas has been suggested. However, studies assessing the role of HCV infection separately in different forms of MALT lymphomas are not available. PATIENTS AND METHODS The prevalence and clinical implications of HCV seropositivity were analyzed in 55 patients with ocular adnexa lymphoma (OAL) of MALT-type. RESULTS...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید