The ability of a member of a new class of lipophilic muramyl dipeptide (MDP) derivative, muramyl dipeptide-glyceryldipalmitate (MDP-GDP), to induce alveolar macrophage cytotoxic activity in vitro towards B16 melanoma cells when incorporated into two types of liposome was studied. MDP-GDP incorporated into conventionally prepared liposomes formulated from distearoylphosphatidylcholine and phosph...

Freeze-dried systems (L) comprising chitosan (CS) and caffeine (CAF) have been developed for oral administration. Different proportions of CS and CAF have been used in the preparation of the systems. Hot stage microscopy (HSM), differential scanning calorimetry (DSC) and X-ray diffraction powder have been used to characterize the systems prepared. X-ray diffraction patterns showed that there we...

The aim of the study was to evaluate the efficiency of an ultrasonic pretreatment at different amplitudes and extraction times, on the content of antioxidant compounds (phenolics, anthocyanins, ascorbic acid) and total antioxidant capacity of black currant fruits. Additionally, the influence of sample preparation (frozen storage/drying) was evaluated. Extraction was performed in 60% ethanol wit...

9 Abstract The drying process of fresh plant materials may 10 affect the porous structure, dehydration and a number of 11 quality characteristics of these materials. Therefore, this 12 study has investigated the effect of different drying pro13 cesses on the variation of metal and metalloid concentra14 tions in the dried plant materials. Seven varieties of native 15 plant species collected from...

objectives: probiotic approaches are being considered to eliminate pathogenic microorganisms and are an alternative and promising way to combat infections by using harmless bacteria to displace pathogenic microorganisms. the aim of this study was to evaluate the effectiveness of commercially available freeze dried powdered probiotics on mutans streptococci count among 12-15 year-old indian scho...

Freeze-drying is a well-known dehydration method widely used to preserve microorganisms. In order to produce freeze-dried yeast starter culture for the brewing purpose of African sorghum beer, we tested protective agents (sucrose, glucose, glycerol) in combination with support materials (millet, maize, sorghum, and cassava flours) at 1:1 ratio (v/v). The yeast strains Saccharomyces cerevisiae F...

Foam-mat drying is an alternative method which enables the removal of water from high-sugar content juices and purees that are difficult to dry. The aim of this study was to investigate the effect of different foam-mat drying methods on some physical properties and aroma of apple puree powder. Apple puree was foamed with the addition of foaming agents. Foamed puree was dried as a layer using di...

The effects of air-drying and freeze-drying on the extraction yields and quality of oils from Quebec sea buckthorn (cv. Indian-summer) seeds and pulp were studied. Oil extractions were carried out using hexane. Air-dried (ADS) and freeze-dried (FDS) seeds, gave a similar extraction yields ( 12% w/w), whereas those of air-dried (ADP) and freeze-dried (FDP) pulps were significantly different (35....

The suitability of freeze-dried plasmas from patients on oral anticoagulants to serve as reference material in the calibration of thromboplastins used in the control of oral anticoagulant treatment was assessed in two centres. One pooled normal plasma and four pooled plasmas from patients at different levels of anticoagulation were collected into HEPES-citrate containing Trasylol. The plasmas, ...

Nanospheres of poly(methacrylic acid-grafted-poly(ethylene glycol)) were prepared by solution/precipitation polymerization. As colloidal drug delivery carriers, they present unique properties that render them promising candidates for oral protein delivery. The polymerization was carried out in water and the resulting suspension was freeze-dried. As with many colloidal systems, the freeze-dried ...