The folate receptor (FR) is overexpressed on a variety of tumor types, whereas its distribution in normal tissues and organs is highly limited. Exploration of the utility of the FR revealed its promising potential for targeting with folate-based radiopharmaceuticals. Herein, we report the principle of the FR-targeting strategy and summarize the development of several folic acid radioconjugates ...

Our earlier efforts to document the cortical connections of the ventral premotor cortex (PMv) revealed dense connections with a field rostral and lateral to PMv, an area we called the frontal rostral field (FR). Here, we present data collected in FR using electrophysiological and anatomical methods. Results show that FR contains an isolated motor representation of the forelimb that can be diffe...

Developmental responses associated with end-of-day far-red light (EOD-FR) signaling were investigated in maize (Zea mays subspecies mays) seedlings. A survey of genetically diverse inbreds of temperate and tropical/semitropical origins, together with teosinte (Zea mays subspecies parviglumis) and a modern hybrid, revealed distinct elongation responses. A mesocotyl elongation response to the EOD...

With the aim of exploring the properties of the class of FR 0 radio galaxies, we selected a sample of 108 compact radio sources, called FR0CAT, by combining observations from the NVSS, FIRST, and SDSS surveys. We included in the catalog sources with redshift ≤ 0.05, with a radio size . 5 kpc, and with an optical spectrum characteristic of low-excitation galaxies. Their radio luminosities at 1.4...

This randomized controlled trial investigated whether adding the psychodynamically based body-oriented psychotherapy "Functional Relaxation" (FR) to psychoeducation (PE) is more effective than PE alone to reduce stress and stress-associated complaints. Eighty-one participants with elevated stress-levels, ≥50 points on the global scale of the Perceived Stress Questionnaire (PSQ), received either...

Food restriction (FR) is the only known intervention capable of increasing mammalian life span. It not only increases longevity, but reduces the incidence of a broad spectrum of age-related pathologies, including cardiomyopathy, and retards the physiological decline associated with aging. Previous work from this laboratory has shown that long-term FR affects the contractile machinery of the hea...

Maternal undernutrition in pregnancy is associated with intrauterine growth restriction (IUGR). With enhanced nutrient support, IUGR newborns may demonstrate a rapid catch-up growth and, paradoxically, the development of obesity in adult offspring. As hypothalamic control of appetite is likely set during the fetal or neonatal period, nutrient stress and perhaps nutrient enhancement during these...

Maxime Lenormand, ∗ Thomas Louail, 3 Marc Barthelemy, 5 and José J. Ramasco Irstea, UMR TETIS, 500 rue François Breton, FR-34093 Montpellier, France Instituto de F́ısica Interdisciplinar y Sistemas Complejos IFISC (CSIC-UIB), Campus UIB, ES-07122 Palma de Mallorca, Spain CNRS, UMR 8504 Géographie-Cités, 13 rue du four, FR-75006 Paris, France Institut de Physique Théorique, CEA-CNRS (URA 2306), F...

The vulnerability of deep-learning based face-recognition (FR) methods, to presentation attacks (PA) is studied in this paper. Recently proposed FR methods based on deep neural networks (DNN) have been shown to outperform most other methods by a significant margin. In a trustworthy face-verification system, however, maximizing recognition-performance alone is not sufficient – the system should ...

A series of flame-retardant nanocomposites were established based on compounding of natural rubber (NR) and dendrimer modified flame-retardant organic montmorillonite (FR-DOMt). The merits of these nanocomposites were focused on their better mechanical and flame-retardant properties. X-ray diffractometer (XRD) together with scanning electron microscopy (SEM) and transmission electron microscopy...