Introduction: The French clinical research network is a platform called “Plateforme Nationale de Recherche Clinique” (PNRC), it was created in 2009 under the guidance of patients’ organisation Vaincre la Mucoviscidose and investigators from ECFS-CTN to promote CF France. Objectives: We aim describe 1) most relevant actions carried out by since 2009; 2) which pitfalls were encountered how they’v...

from may 1994 to december 1996 thirty patients received viable fresh aortic homografts. mean age was 55 years (13 to 70), male to female ratio was 2/1, 24 operations were elective whereas 6 were semiurgent. predominant lesions were aortic stenosis or regurgitation in lb patients, aortic valve endocarditis in 10, prosthetic valve dysfunction in 3, and aortic root pathology in one patient. from t...

brain tumors are considered in regarded to their size, position and aggressive manner. brain tumors cause several neurologic symptoms. for instance, they increase intracranial pressure due to local damage and displacement of surrounding tissues. in this paper, two glioblastoma multiform cases with more than 15 year- survival have been reported. the first patient was a 52 year- old woman who suf...