BACKGROUND Diabetes is becoming one of the most common chronic diseases, and ulcers are its most serious complication. Beginning with neuropathy, the subsequent foot wounds frequently lead to lower extremity amputation, even in the absence of critical limb ischemia. In recent years, some researchers have studied external shock wave therapy (ESWT) as a new approach to soft tissue wound healing. ...

“Early intervention in order to prevent potential disaster in the management of Diabetic foot is not only a great responsibility, but also a great opportunity” Despite advances in our understanding and treatment of diabetes mellitus, diabetic foot disease still remains a terrifying problem. Diabetes is recognized as the most common cause of non-traumatic lower limb amputation in the western wor...

Podocytes are highly specialized epithelial cells located at the outer aspects of the glomerular capillary tuft and critical components of the kidney filtration barrier. To maintain their unique features, podocytes express a number of proteins that are only sparsely found elsewhere in the body. In this study, we have identified four (Tmem234, Znf185, Lrrc49, and Slfn5) new highly podocyte-enric...

BACKGROUND To enhance the acute management of people with diabetic foot disease requiring admission, an extended scope of practice, podiatric high-risk foot coordinator position, was established at the Great Western Hospital, Swindon in 2010. The focus of this new role was to facilitate more efficient and timely management of people with complex diabetic foot disease. The aim of this project wa...

Glomerular epithelial cells (podocytes) play an important role in the pathogenesis of proteinuria. Podocyte foot process effacement is characteristic for proteinuric kidneys, and genetic defects in podocyte slit diaphragm proteins may cause nephrotic syndrome. In this work, a systematic electron microscopic analysis was performed of the structural changes of podocytes in two important nephrotic...

With the increasing prevalence of diabetes in the community, morbidity and mortality as a result of diabetic feet has been increasing. Foot complications are one of the most serious and yet preventable complications of diabetes mellitus having an economic impact to the individual and adding the burden to the already inadequate healthcare resources. Complications associated with diabetes are oft...

This activity aims to provide information about FMD breeders in Picisan Village, Sendang District, Tulungagung Regency. village is a with the majority of population as breeders. The observation results showed that there were cows infected but only few had been vaccinated. method implementing this interactive socialization. was carried out by inviting speaker from Animal Husbandry Department and...

Diabetic foot ulceration is both preventable and treatable. The management of diabetic foot disease is best achieved through implementation of local protocols involving the primary care team, community care and the multidisciplinary diabetic team. It is important that the feet the assessed as part of the overall assessment of a diabetic patient at any clinical presentation. The initial manageme...