The immune response of pigs to one and two injections of Waldmannand Frenkel-type monovalent FMD type C vaccines and to experimental infection with FMD type C virus was studied. Neutrali­ zing serum antibody titres were determined, and challenge infections were performed 4 and 8 weeks after the first vaccination, and 2 weeks after the second one; essentially the same schedule was followed with ...

The pathogenesis of foot-and-mouth disease (FMD) is reviewed, taking account of knowledge gained from field and experimental studies and embracing investigations at the level of the virus, the cell, the organ, the whole animal and the herd or flock. The review also addresses the immune response and the carrier state in FMD. Progress made in understanding the pathogenesis of the disease is highl...

On March 20, 2000, a suspected vesicular disease in cattle was reported to the National Veterinary Research and Quarantine Service (NVRQS) of the Republic of Korea. This represented the index case of a foot-and-mouth disease (FMD) outbreak, which spread through several provinces. The Republic of Korea had been free of FMD for 66 years prior to the reintroduction of the virus and had recently su...

OBJECTIVES This study aims to develop a method for calculating infection time lines for disease outbreaks on farms was developed using the 2010/2011 foot-and-mouth disease (FMD) epidemic in the Republic of Korea. METHODS Data on farm demography, the detection date of FMD, the clinical history for the manifestation of lesions, the presence of antibodies against FMD virus (including antibodies ...

Foot-and-Mouth Disease (FMD) is a clinical syndrome in animals due to FMD virus that exists in seven serotypes, whereby recovery from one sero-type does not confer immunity against the other six. So when considering intervention strategies in endemic settings, it is important to take account of the characteristics of the different serotypes in different ecological systems. FMD serotypes are not...

FMD serotype “O” with subtype PAN Asia-II, “A” Tur-06 and “Asia-1” Sindh-08 were adapted on the LFBK cell line subsequently BHK-21. After inactivation these subtypes introduced for development of oil based trivalent vaccine against FMD. The study was conducted experimental animals (cow calves) at Livestock Production Research Institute (LPRI), Okara. Twenty one unvaccinated cattle calves age gr...

A survey of type O foot and mouth disease (FMD) virus isolates from northern Thailand was undertaken to determine the relationship between field viruses and the vaccine in use, and to gauge the range of antigenic variation among field viruses. Isolates were collected from the two most recent epizootics, 1986-1987 and 1989-1990, and assessed using a two-dimensional neutralisation test to determi...

Introduction Foot-and-mouth disease (FMD) is a highly contagious viral disease resulting in tremendous economical losses. In order to minimize the risks of an FMD outbreak in disease-free countries due to animal imports, rapid and reliable screening of sera from susceptible animals for the presence of FMD virus (FMDV) antibodies is necessary. The reasons for the development of a novel FMDV anti...

ABSTRAK Mata pencaharian masyarakat Desa Panggungasri adalah pertanian dan sebagian besar dari mereka memiliki hewan ternak sapi kambing. Memiliki memang memberikan manfaat bagi pemiliknya, namun adanya virus penyakit yang mengancam, secara ekonomi dapat merugikan para peternak di desa. Salah satunya yaitu Penyakit Mulut Kuku (PMK). ini menular dengan menyerang berkuku belah, baik maupun liar s...

In 1898, foot-and-mouth disease (FMD) earned a place in history as the first disease of animals shown to be caused by a virus. Yet, despite over a century of active investigation and elucidation of many aspects of FMD pathogenesis, critical knowledge about the virus-host interactions is still lacking. The aim of this review is to provide a comprehensive overview of FMD pathogenesis in cattle sp...