Agonists induce Ca2+ spikes, waves and oscillations initiating at a trigger zone in exocrine acinar cells via Ca2+ release from intracellular Ca2+ stores. Using a low affinity ratiometric Ca2+ indicator dye, benzothiazole coumarin (BTC), we found that high concentrations of agonists transiently increased Ca2+ concentrations to the micromolar range (>10 microM) in the trigger zone. Comparison wi...

Aquifer drainage was numerically simulated by a coupled, unsaturated-saturated flow equation. The effect of the vadose zone on aquifer parameter predictions of classical hydraulic theory was investigated. Saturated-zone hydraulic theory was shown to be fairly robust in estimating the saturated hydraulic conductivity but less so in estimating drainable porosity, mainly because of the much tighte...

abstract background: transcranial doppler ultrasonography results have not been previously studied in among iranian sickle cell anemia patients. the present study was performed to evaluate the pattern of intracranial flow velocities among iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial art...

A"CLOSED" method for the accurate measurement of myocardial blood flow is still to be achieved. In 1956, Henly et al. described an indicator-dilution technique for assessing myocardial blood flow. This approach led us to construct a suitable model for simulating a systemic-coronary circuit. Observations with this system suggested that an indicator-dilution technique might be applicable to measu...

The current concept for high-level radioactive waste disposal at Yucca Mountain is for the waste to be placed in underground tunnels (or drifts) in the middle of a thick unsaturated zone. Flow modeling and field testing have shown that not all flow encountering a drift will seep into the drift. The underlying reason for the diversion of unsaturated flow around a drift is that capillary forces i...

In this research, the effects of parameters include tool rotational and traverse speeds were investigated on heat generation and material flow during friction stir welding of Ti-6Al-4V alloy with computational fluid dynamics (CFD) method. Simulation results showed that with increasing of tool rotational and decreasing tool traverse speed, the more frictional heat generates which causes formatio...

STUDY DESIGN Retrospective study. PURPOSE To evaluate the initial fixation using the cortical bone trajectory (CBT) technique for posterior lumbar fusion through assessment of the clear zones around the screws and the risk factors involved. OVERVIEW OF LITERATURE Postoperative radiolucent zones (clear zones) are an indicator of poor conventional pedicle screw fixation. METHODS Between Jan...

–Previous electrophysiological studies in pigeons have shown that the vestibulocerebellum can be divided into two parasagittal zones based on responses to optic flow stimuli. The medial zone responds best to optic flow resulting from self-translation, whereas the lateral zone responds best to optic flow resulting from self-rotation. This information arrives from the retina via a projection from...