Although many highly active antiretroviral therapy (HAART) regimens using 3 drugs have demonstrated potent and durable antiretroviral effects, cohort studies have shown that treatment failure occurs in about 30% to 50% of patients. This failure rate prompts a closer look into the causes of treatment failure and how to modify or overcome these causes with new and more effective therapeutic regim...

starch could used as ingredient fillers, binders and crushers in tablet manufacture. Amylum is also defined carbohydrates from plant, results photosynthesis, which stored part certain plant backup food mixture two type structure different polysaccharides that contains (17-20) % amylose (80-83) amylopectin. Destination study this for know the formulation of mucoadhesive tablets with fully gelati...

Introduction Oral controlled release (CR) dosage forms generally have a transit time of 1–3 hours in the stomach,3–5 hours in the intestine and 4–11 hours in the colon(1). However,some drugs require more retention time in the stomach for better results. Gastro-retentive drug delivery is superior for drugs such as (a) drugs having a narrow absorption window,(b) drugs having their local effect in...

the main objective of the present study was to formulate gastroretentive effervescent sustained release drug delivery systems of risperidone floating tablets with the help of methocel® k15, ethocel® standard 7fp premium, eudragit ® rs100 sustained release polymers to improve its safety profile, bioavailability and patient compliance. risperidone floating tablets were formulated by wet granulati...

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X-ray crystallographic studies have been carried out on three compounds containing chromium-chromium quadruple bonds: Cr2(02CCH&(H02CCH&, I, C ~ ~ ( O ~ C C H ~ ) ~ ( C S H , , N ) ~ , 11 and [NHI]~[C~~(CQ~)~(M~~)~](H~~)~-~, III. The results, together with those on nine compounds in the literature, are sufficient to indicate a crude general relationship between the donor ability of the bridging...