BACKGROUND AND OBJECTIVES Vascular photodynamic therapy (PDT) inhibits intimal hyperplasia (IH) induced by angioplasty in rat iliac arteries by eradicating the proliferating smooth muscle cells. This process may jeopardise the structure and strength of the arterial wall, reflected by a decreased bursting pressure. STUDY DESIGN/MATERIALS AND METHODS Thirty male Wistar rats of 250-300 g were su...

An elevation of potassium content of the aorta is found in renal hypertensive rats. Reduction of hypertension by potassium deprivation is followed by a proportional decrease in the aorta potassium content. Restoration of hypertension in such rats by cortisone administration is associated with a return of the aorta potassium content to the previous elevated levels. It is suggested that the potas...

Regulation of the flow and movement of water is essential to the health and well-being of our bodies. Involving a diverse array of structures that range from molecular gatekeepers to tissue barriers, water flow and concentration are maintained at precise levels. However, in many instances we do not have a complete picture of how this works. A case in point is the arterial wall, which separates ...

Atherosclerotic change of the arterial wall leads to a significant change in its elasticity. For assessment of elasticity, measurement of arterial wall deformation is required. For motion estimation, correlation techniques are widely used, and we developed a phase-sensitive correlation method, namely, the phased-tracking method, to measure the regional strain of the arterial wall due to the hea...

Wall Viscosity of the Stented Arteries To the Editor: In the November 2003 issue of Stroke, Vernhet and colleagues reported a clinical analysis of wall mechanics in stented extracranial carotid arteries, and they concluded that stenting of these arteries induces a compliance mismatch between the native and the stented artery. Additionally, the authors observed a significant decrease in the dist...

The current study is based on an examination of the effect Newtonian blood flow value wall shearing stress intracranial aneurysm using computational fluid dynamics. Blood frequently thought to behave like a in cerebral arteries. It fully described how saccular affects model blood-silver (Ag) nanofluid via artery. regarded as because its rheology. Newtonian, laminar, incompressible, viscous, and...

The goal of this study was to review the origin, clinical relevance and treatment of pulse pressure (PP). Elevated PP is increasingly being recognized as a risk factor for cardiovascular, particularly coronary, disease. Pulse pressure is discussed in terms of both Windkessel and distributive models of the arterial circulation. Pulse pressure arises from the interaction of cardiac ejection (stro...

Arachidonic acid, the precursor of all bisenoic prostaglandins, is the most common fatty acid present in cellular phospholipids and can be obtained directly from the diet or by desaturation and chain elongation from dietary linoleic acid (C18:2 w-6). Arachidonic acid is liberated from membrane phospholipids by the action of phospholipases, activated by changes in their chemical environment. Sim...

Background Coronary thrombosis is a dynamic process dependent on the pathological substrate, the local shear forces, and blood factors. Methods and Results We investigated the effect of a severe (80%) eccentric stenosis on fibrin(ogen) interaction with a deeply damaged vessel wall, its relation to platelet deposition in thrombus formation, and the influence of time on thrombus growth. Porcine '...