Achieving high-performance while reducing power consumption is the key question as technology scaling is reaching its limits. It is well-accepted that application-specific custom hardware can achieve orders of magnitude improvements in efficiency. The question is whether such efficiency can be maintained while providing enough flexibility to implement a broad class of operations. In this paper,...

A new matrix factorization algorithm which combines two recently proposed nonnegative learning techniques is presented. Our new algorithm, α-PNMF, inherits the advantages of Projective Nonnegative Matrix Factorization (PNMF) for learning a highly orthogonal factor matrix. When the Kullback-Leibler (KL) divergence is generalized to αdivergence, it gives our method more flexibility in approximati...

The ability to print and pattern all the components that make up a tissue (cells and matrix materials) in three dimensions to generate structures similar to tissues is an exciting prospect of bioprinting. However, the majority of the matrix materials used so far for bioprinting cannot represent the complexity of natural extracellular matrix (ECM) and thus are unable to reconstitute the intrinsi...

We propose a new input perturbation mechanism for publishing a covariance matrix to achieve ( , 0)differential privacy. Our mechanism uses a Wishart distribution to generate matrix noise. In particular, we apply this mechanism to principal component analysis (PCA). Our mechanism is able to keep the positive semi-definiteness of the published covariance matrix. Thus, our approach gives rise to a...

We discuss computationally efficient and numerically reliable algorithms to compute minimal proper nullspace bases of a rational or polynomial matrix. The underlying main computational tool is the orthogonal reduction to a Kronecker-like form of the system matrix of an equivalent descriptor system realization. A new algorithm is proposed to compute a simple minimal proper nullspace basis, start...

Copper(I) halides have been successfully established as a preparative tool for the synthesis of neutral and low-charge molecules of the fifth and sixth main-group elements. Inspired by publications of Rabenau et al. as well as M$ller and Jeitschko, a whole series of phosphorus, phosphorus chalcogenide, and heteroatomic chalcogen molecules were obtained in a copper halide matrix. Mixed phosphoru...

Antibodies are a key element in immunoassays They are the driving force behind specificity and sensitivity. Affinity purification of antiserum yields antibodies with the ultimate in specificity and sensitivity. It eliminates all other potentially interfering serum proteins and antibodies that will increase the background and cause cross-reactivity. It leaves behind a population of antibodies th...

Software reuse is commonly used to leverage existing assets and to reduce development cost and time. Reuse can be accomplished by several different mechanisms. This paper describes these mechanisms and proposes a classification framework for them. The framework has two dimensions: retest scope⎯how the reuse impacts the need for testing⎯and binding time⎯when the reuse is realized. By examining t...

Modern information systems contain many mechanisms for implementing authorization and thus are capable of meeting a given authorization requirement with many designs. Each design carries a set of properties that directly impact users, such as administrative effort, risk of compromise, and flexibility. The property matrix method is a method to capture the user requirements for these properties, ...