BACKGROUND AND AIMS Epidermal growth factor (EGF) is a potent mitogen for the gastrointestinal tract and also influences the number of new crypts formed by crypt fission. The time course of these events and possible linkage between these two complementary mechanisms is however poorly understood. We therefore examined the temporal relationship of proliferation and fission in rats treated with EG...

Fission gas plays a significant role in fuel rod performance following accidents. The amount of fission increases dramatically under accidental conditions. This leads to subsequent rise the internal pressure and temperature due aggravated gap conductance between pellet cladding. As result, degrades. Therefore, studying behavior is crucial for accident assessment evaluating performance. Minimizi...

The explanation of the asymmetry in the fragment mass distributions of many actinide nuclei has long been a stumblestone in fission theory. Shortly after the advent of the shell model, Lise Meitner related the mass asymmetry to shell structure, in particular to magic nucleon numbers in one of the fragments. Indeed, since the classical liquid drop model (LDM) prefers symmetric shapes, the mass a...

With few exceptions the endoplasmic reticulum (ER) is considered a continuous system of endomembranes within which proteins and ions can move. We have studied dynamic structural changes of the ER in hippocampal neurons in primary culture and organotypic slices. Fluorescence recovery after photobleaching (FRAP) was used to quantify and model ER structural dynamics. Ultrastructure was assessed by...

The cytoplasmic dynamin-related guanosine triphosphatase Drp1 is recruited to mitochondria and mediates mitochondrial fission. Although the mitochondrial outer membrane (MOM) protein Fis1 is thought to be a Drp1 receptor, this has not been confirmed. To analyze the mechanism of Drp1 recruitment, we manipulated the expression of mitochondrial fission and fusion proteins and demonstrated that (a)...

Hans Kruse and William T. Pinkston Department of Physics, Vanderbilt Uniuersity, Nashuille, Tennessee 37235 (Received 23 February 1979) Within an extended semiquantal theory we perform large-sized coupled-channel calculations involving 260 collectiue .levels for Coulomb fission of 238U. Differential Coulomb fission cross sections are studied as a function of bombarding energy and impact Paramet...

BACKGROUND/AIMS Endothelin-1 is implicated in the pathogenesis of hypertension, but the underlying mechanisms remained elusive. Our previous study found that inhibition of mitochondrial fission of smooth muscle cells suppressed phenylephrine- and high K+-induced artery constriction. Here, we studied the effects of mitochondrial fission inhibitors on endothelin-1-induced vasoconstriction. METH...

The common goal of CTR, but in particular of ICF, is low yield-high gain. Fission triggered large TN explosive devices meet the second but not he first of these conditions. These devices depend on the rare isotopes U235, Pu239, or U233, but for them the fusion energy output greatly exceeds the output from fission, limiting the fallout. In thinking about different ways to combine fusion with fis...

The shortest path problem is solved and applied to the calculations of half lives with respect to spontaneous fission of heavy nuclei. The dynamical programming method of Bellman and Kalaba is used to find the fission path in the d-dimensional space of deformation parameters. Fission half lives of heavy isotopes (100<Z<110) are shown and compared to the experimental data. 1. Introductory remark...

The shortest path problem is solved and applied to the calculations of half lives with respect to spontaneous fission of heavy nuclei. The dynamical programming method of Bellman and Kalaba is used to find the fission path in the d-dimensional space of deformation parameters. Fission half lives of heavy isotopes (100<Z<110) are shown and compared to the experimental data. 1. Introductory remark...